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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
    October 14, 2011 - The Key Questions The overarching question to be addressed in our systematic review is the following … One commentator addressed the value of PCA3 test results in multispecialty team decisionmaking and … Was there a comprehensive literature search that adequately addressed the KQs, included at least two … Was potential conflict of interest addressed by acknowledging sources of support in the systematic review
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
    June 01, 2011 - These addressed a variety of clinical conditions. … These addressed a variety of conditions—chronic noncancer pain,1 sexually transmitted infections (STIs … Research gaps were identified as the key questions that were addressed by only "poor-quality" evidence … Those elements which are inadequately addressed in the evidence base should be characterized. … Those elements which are inadequately addressed in the evidence base should be characterized.
  3. Schwitzer_ECCS2012 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/schwitzer_eccs2012.pdf
    July 23, 2012 - results,  overdiagnosis of breast cancer, or a diagnosis of ductal carcinoma in situ, however, is not addressed
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
    May 01, 2012 - the study design is sound and the above assumptions hold sufficiently that the primary issue to be addressed … across a relevant range of patient characteristics, then the effect of confounding by indication can be addressed … methods to address the problem of confounding while promoting transparency in how the confounding was addressed … Missing Data Missing data within the source data set will need to be addressed in order to retain … is used, the explicit choice of the comparison group(s) to address the research question should be addressed
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
    January 27, 2016 - Most of the studies only addressed antibiotic use or not. … But this reviewer doesn’t have any additional thoughts on how this issue could be better addressed. … However a few issues need to be addressed first. … Future research needs were addressed. 226. … There are key conceptual problems that could be addressed to enhance the impact of this substantial
  6. Ced-Appendix-3 (xls file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
    June 24, 2022 - history and preexisting conditions, as well as followup information needed evaluate the question being addressed … FDA2021 Data Continuity of coverage (enrollment and disenrollment) should be addressed when using EHR … years covered FDA2021 Data_sufficiency Continuity of coverage (enrollment and disenrollment) should be addressed … history and preexisting conditions, as well as followup information needed evaluate the question being addressed
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
    May 01, 2019 - The specific Key Questions (KQs) addressed in this review are listed below, and Figure A displays the … PCOS We identified 61 articles42-102 describing 56 studies that addressed the comparative safety and … Endometriosis We identified seven individual studies that addressed infertility treatment for women … and Peritoneal Factor Infertility We identified eight individual studies90,91,111,161-165 that addressed … four retrospective observational studies, three fair- quality,183-185 and one poor-quality,186 that addressed
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
    May 01, 2022 - The 2020 report addressed benefits and harms of opioid, nonopioid pharmacologic, and nonpharmacologic … The report addressed the following acute pain conditions: • Acute back pain (including back pain with … 7) • Sickle cell crisis (episodic pain) (KQ 8) For each of these acute pain conditions, the report addressed … The report also addressed how benefits and harms varied according to demographic, clinical, and medication … Five trials6,7,9-11 addressed acute (non-dental) postoperative pain and two5,8 addressed acute post-surgical
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/primary-healthcare-spending-disposition-comments.pdf
    May 17, 2024 - We addressed this. Thank you. … We have addressed this is the revised brief. … We have addressed the need for conducting research to identify the elements of primary care spending … the categories of decision making and the variation in approaches for each of the dimensions are addressed … Measurement challenges associated with multidisciplinary care teams should be more explicitly addressed
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/telehealth-women-protocol.pdf
    June 21, 2021 - present opportunities to close the gap on these disparities.29 Yet, research has not definitively addressed … Harms (KQ1f and 2f) will also be addressed. … reviewed by Agency for Healthcare Research and Quality (AHRQ) staff and the HRSA partner to ensure they addressed
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-disposition-comments.pdf
    January 14, 2025 - lens by agencies working with children exposed to trauma with measurable levels of distress is not addressed … trauma-focused treatments and interventions will be far from clarified by the report despite being addressed
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_executive.pdf
    September 01, 2014 - The Key Questions addressed in the original report and this updated report are as follows: Key Question … Ten new cohort studies and one new nested case-control study addressed the association of serum 25(OH … Colorectal Cancer No new RCTs and cohort studies that addressed the effect of vitamin D on colorectal … and Calcium and All-Cause Mortality No new studies were identified for the current report that addressed … The current report addressed body weight only in infants and did not address the effects of calcium.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
    May 27, 2014 - These issues have been addressed (where they are called out specifically below). … We feel that KQ3 has been addressed in as much detail as the literature allows, but agree that we found … (see above) We addressed this concern above: “The vast majority of studies do not differentiate … We have addressed this in the Discussion section. … The major issue not addressed is the potential difference between patients with HFrEF and HFpEF This
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
    June 12, 2012 - We received few actionable comments, and none required revisions to the KQs: One comment addressed the … Circles on the diagram indicate areas in which KQs will be addressed in the review. … current CER and augment the summary with results of studies meeting our inclusion criteria and not addressed … Risk of bias is derived from the quality assessment of the individual studies that addressed the KQ … Low □ Unclear Other bias Other sources of bias Any important concerns about bias not addressed
  15. effectivehealthcare.ahrq.gov/sites/default/files/tympanostomy-tubes-disposition.pdf
    May 05, 2017 - We have addressed specific comments by this reviewer related to our use of different approaches tailored … As noted below, there are a few issues that could be addressed to make the report even better, but … children with TT) vs applicability, which I believe would apply to specific groups of children not addressed … In general: I don’t think this part of KQ1 was addressed: Does obtaining a hearing test help identify … Peer Reviewer #1 Results Page 69 First paragraph: Was hearing addressed here as an outcome, and
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-disposition.pdf
    May 05, 2017 - We have addressed specific comments by this reviewer related to our use of different approaches tailored … As noted below, there are a few issues that could be addressed to make the report even better, but … children with TT) vs applicability, which I believe would apply to specific groups of children not addressed … In general: I don’t think this part of KQ1 was addressed: Does obtaining a hearing test help identify … Peer Reviewer #1 Results Page 69 First paragraph: Was hearing addressed here as an outcome, and
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
    February 25, 2014 - This is a problematic part of the report that needs to be addressed before publication. … important and it was a strength that the limitations surrounding the NRT studies were adequately addressed … It needs to be directly addressed by this Report. … It is surprising that breastfeeding was not controlled for in the analyses or addressed in the report … We have addressed the need for future research, including replication of promising studies, in the
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
    February 01, 2018 - recommendations were codified in 2010 as a chapter in the AHRQ EPC Program Methods Guide.8 Issues addressed … information on the most critical outcomes.12 Review of EPC Reports We reviewed 18 EPC reports that addressed … informal process (e.g., soliciting general feedback from a panel of stakeholders on outcomes to be addressed … or prioritization of harms in EPC reviews is an important challenge that has not previously been addressed … question on the interview (you can provide additional comments after the call via email for questions not addressed
  19. effectivehealthcare.ahrq.gov/sites/default/files/celiac-disease_disposition-comments.pdf
    January 28, 2016 - General Comments It should be noted that certain relevant questions related to this review are not addressed … Methods The overarching issue of how to best find celiac diagnosis in the general population is not addressed … Population Screening One area of study that is alluded to in the conclusions, but is not really addressed
  20. effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
    January 01, 2010 - that may be associated with the outcome, such as confounders or effect modifiers, which also must be addressed … distinguish short-term use from long-term use so that the primary study question can be adequately addressed … should be related back to the conceptual framework and biological plausibility of the question being addressed

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