-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
November 20, 2014 - It does not address the
number of lesions per patient or per study. … Yes, we attempted to address technical
variations in Key Questions 1.e.iii and 2.e.iii;
however, we … General Comments: This report addresses a clinically important
question as to the optimal staging methodology … The report does address changes in
management as one of the key questions. … these as
stage reclassification and changes in therapeutic management.7 In
addition, the Draft Report addresses
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
September 01, 2008 - insulin
analogs to combination regimens of long- and rapid-acting insulins that could potentially address … NPH has no
way whatsoever to address postprandial changes in glucose. Ity is non physiological. … However, we can expect that the premixed insulin analogues will address post-breakfast and post-dinner … One of these addresses
primarily fasting; the other addresses primarily post prandial. … We would also like to take this opportunity to inform AHRQ of ongoing studies that address key
gaps
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_disposition-comments.pdf
December 14, 2015 - We have attempted to address all issues
identified by the reviewer. … To
address this issue, we have attempted to better
highlight the report’s clinical messages in the … To
address this issue, we have attempted to better
highlight the report’s clinical messages in the … The review does not address the time
pressures for diagnosis and the methods of
diagnosis in a widely … We hope to address this to some
extent by seeking the publication of a separate peer-
reviewed paper
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
June 23, 2011 - Other reviews in the
series will address a range of quality improvement topics arising from Agency for … KQ 1 addresses how
different potential responses affect study outcomes, including health care spending … Criteria for Inclusion/Exclusion of Studies in the Review
Studies will be included that address the … The bundled payment intervention meets other inclusion criteria and the study
addresses the key study
-
effectivehealthcare.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
January 01, 2012 - treatments, screening and diagnostics, therapeutics, surgery, programs, and care
delivery innovations that address … The system is intended
to identify interventions that purport to address an unmet need and are up to … To address the need for more effective cessation tools, Voxiva, Inc.,
and The George Washington University … Long-acting formulations of these pharmacotherapies
might address these issues. … buprenorphine (Probuphine
™
, Titan Pharmaceuticals, Inc., South San Francisco, CA) is
under study to address
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
February 01, 2015 - treatments, screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations that address … The system
is intended to identify interventions that purport to address an unmet need and are up to … If effective, it may address this
unmet need, as a well-tolerated, potentially disease-modifying treatment … treating AD-related cognitive symptoms; they also concluded that intranasal insulin
could possibly address … treatments for AD, they were not overly optimistic that intranasal
insulin has high potential to address
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_disposition-comments.pdf
July 03, 2012 - This addresses all of these
comments. … All the reviewed studies need to address their usefulness in clinical
decision making. … In my opinion, the report doesn't address the
"possible" value but rather "the value of current SNP
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
May 08, 2013 - Omitting these findings would be an error...the
studies are not well designed but address a huge area … Peer Reviewer
#6
Results
Page 76, please address somewhere how allocation to visible
devices … It does not address common clinical issues, I
have highlighted them in my comments. … important information, especially when
RCT's are not feasible, not available, or insufficient to
address … WCET 2010, 30(3):20-22
This is a study on prevalence/incidence that does not
address any of the key
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
October 23, 2014 - We revised this to be clearer that KQ 1 addresses
detection of HCC in surveillance and non-surveillance … We revised KQ 1 to be clearer that it addresses
detection of HCC in surveillance and non-surveillance … To address
heterogeneity we performed many stratified/sensitivity
analyses and also focused on direct … An evidence
review funded by the VA was recently completed and
addresses issues around screening in … Peer Reviewer
#5
General The report addresses an important topic with key questions clearly stated
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow-disposition-170415.pdf
January 12, 2017 - Will need to address this in all
pertinent sections of the methods. … We revised the text to address the specific
methods issues brought up in separate
comments. … Observational studies that address
confounders could be designed, and, given the
equipoise between … purpose of the report is to compare the tGCS
vs. more abbreviated versions of the GCS; we
did not address … inadvertently left
in Key Question 2a; we had previously revised
Key Question 2 to more specifically address
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
October 30, 2012 - objective outcome definitions that correspond to the
nature of the hypothesized treatment effect and address … Use of appropriate analytic methods suitable to the outcome measure and sensitivity analysis to
address … To address the interrelationships of
these outcomes, some conceptual models have
been put forth by … FDA addresses content validity as being
of primary interest in assessing a PRO, with other
measurement … o
Address issues of bias
expected to arise, and
propose means of bias
minimization.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
February 01, 2018 - EPC reviews frequently address many interventions, which could result in many
potential harms (e.g., … events”), which might facilitate comparisons between
interventions with dissimilar harms, and how to address … depending on your input and direction of the interview we
may ask additional questions and may not address
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
November 24, 2014 - assess selection bias,
confounding, performance bias, detection bias, and attrition
bias—that is, it addresses … assess selection bias, confounding, performance
bias, detection bias, and attrition bias—that is, it addresses … We have
included suggestions of study designs to address both clinical
and microbiological outcomes … in
well defined patient populations, experiencing infection
due to specific pathogens, in order to address … Affiliation Section Comment Final Response
TEP Reviewer
#6
General Comments This review does not address
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
November 01, 2012 - Most studies did not adequately address the problems
of selection bias or attrition. … Better research is
needed to address questions related to LTC delivered
through HCBS versus NH, including … Studies should be
designed to address both methodological issues and
fundamental questions such as … Summary of research gaps to address
Methodological Issues Findings Research Needs
Define interventions … Summary of research gaps to address (continued)
Methodological Issues Findings Research Needs
Other
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0210_12-07-2009.pdf
January 01, 2009 - Forms of
rehabilitation to address the long-term outcomes include physical, behavioral, speech, occupational
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0251_05-20-2010.pdf
January 01, 2010 - From health care professional association:
The nominator is interested in an evidence review to address
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
January 01, 2014 - was identified as an important factor to consider; therefore an additional
subquestion was added to address … We will also include high quality systematic
reviews that address accuracy of the included diagnostic … of rare adverse events will be included
for key question 2, in anticipation that few studies will address … with strength of evidence grades and domains, and the included
original studies12; if multiple SRs address … the same question and are included, we will
construct a matrix to compare included studies to help address
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
January 01, 2011 - No recent review or clinical guidelines were identified that comprehensively address the topic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
May 19, 2011 - We will utilize existing systematic reviews as one component of the report to address the
KQs. … Epidemiology and
End Results (SEER) database and other nationally representative cancer registries to address … The KQs were
reviewed with the TEP to assure that the review explicitly addresses the KQs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
March 10, 2010 - The section on the scope of the key questions addresses this
concern
Introduction Page seven ? … In order to address this issue wording has been
specifically added to remind the reader that the issue … Methods Comment: CER focus on LDL-C does not adequately address role of
combination therapy to treat … number of
studies
Methods Qualitatively, or quantatitively, provide description on how you could
address