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1. Screening for Abdominal Aortic Aneurysm: US Preventive Services Task Force Recommendation Statement (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/HyxpKaXv6BVDKBHQ74yWeL
   December 10, 2019 - who have never smoked and have no family history of AAA. … Family History Family history of AAA in a first-degree relative doubles the risk of developing AAA.25 … In the United States, 80% of intact AAA repairs and 52% of ruptured AAA re- pairs are performed using … never smoked and do not have a family history of AAA. … AAA.

2. Recommendation: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening
   December 10, 2019 - in women who have never smoked and have no family history of AAA. … AAA. … AAA. 25 The risk of developing an AAA is stronger with a female first-degree relative (odds ratio [ … Open repair is a time-tested, effective treatment for AAA. … In the United States, 80% of intact AAA repairs and 52% of ruptured AAA repairs are performed using EVAR

3. Archived: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening-2014
   June 23, 2014 - It detected no difference in the rate of AAA rupture, AAA-specific mortality, or all-cause mortality … Important risk factors for AAA include older age and a first-degree relative with an AAA; other risk … They receive annual surveillance for AAA and peripheral artery disease, and those with an AAA measuring … Only a single screening trial of AAA included women, and it showed no benefit in preventing AAA-specific … Overall, women have a lower prevalence of AAA than men at any age and seem to develop AAA at a later

4. Archived: Final Evidence Summary: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/abdominal-aortic-aneurysm-screening-february-2005
   February 15, 2005 - Study Selection: Randomized trials of AAA population screening, population studies of AAA risk factors … No significant reduction in AAA-related mortality was found in 1 study of AAA screening in women. … 9 AAA Screening in High-Risk Populations Age is a significant AAA risk factor. … to reduce deaths from AAA. … AAA-related death with screening) ) * AAA = abdominal aortic aneurysm; OR = odds ratio.

5. Ym2Epescwzwnpaamr78Shp (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/Ym2epesCwZWNPaaMr78Shp
   August 01, 2014 - history of AAA (17). … They receive annual surveillance for AAA and peripheral artery disease, and those with an AAA measuring … AAA-Related Mortality. … Only a single screening trial of AAA included women, and it showed no benefit in preventing AAA-specific … The USPSTF found adequate evidence that the AAA- specific mortality benefit of screening for AAA in women

6. Clinical Summary: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/ClinicalSummaryFinal/abdominal-aortic-aneurysm-screening
   December 10, 2019 - 75 years who have ever smoked: Grade B Perform 1-time screening for abdominal aortic aneurysm (AAA … : Grade D Do not screen women who have never smoked and do not have a family history of AAA. … in women aged 65 to 75 years who have ever smoked or have a family history of AAA. … AAA. … Abdominal duplex ultrasonography is the standard approach for AAA screening.

7. Archived: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening-february-2005
   February 15, 2005 - A first-degree family history of AAA requiring surgical repair also elevates a man's risk for AAA; this … Screening for AAA would most benefit those who have a reasonably high probability of having an AAA large … of AAA-related deaths in this population. … AAA-specific mortality in older men who undergo screening. … The prevalence of AAA in women was one-sixth of that in men.

8. Screening for Abdominal Aortic Aneurysm - Recommendation Statement (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/p8bwnFstpfy9KoDSJhT7m5
   February 01, 2005 - to decreased AAA-specific mortality. … A first-degree family history of AAA requiring surgical repair also elevates a man’s risk for AAA; this … • Screening for AAA would most benefit those who have a reasonably high probability of having an AAA … number of AAA-related deaths in this population. … • Open surgical repair for an AAA of at least 5.5 cm leads to an estimated 43% reduction in AAA-specific

9. Screening for Abdominal Aortic Aneurysm: Clinical Summary of USPSTF Recommendation (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/qns4u8H9_JgDHNje6by4dZ
   Grade: B Selectively screen for AAA. Grade: C No recommendation. … Grade: I statement Do not screen for AAA. … Grade: D Risk Assessment Risk factors for AAA include older age; a positive smoking history … Screening Tests Abdominal duplex ultrasonography is the standard approach for AAA screening. … Short-term treatment with antibiotics or β-blockers does not appear to reduce AAA growth.

10. Clinician Summary of USPSTF Recommendation Screening for Abdominal Aortic Aneurysm (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/SA2xTFXTzgdbgTYw9DEoMS
    December 01, 2019 - men aged 65 to 75 years who have ever smoked Perform 1-time screening for abdominal aortic aneurysm (AAA … never smoked and do not have a family history of AAA. … in women aged 65 to 75 years who have ever smoked or have a family history of AAA. … AAA. … Abdominal duplex ultrasonography is the standard approach for AAA screening. a.

11. 0306 AHRQ AAA_provider F.indd (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/Qww2ewWQGpBxkza9UkSXJA
    April 01, 2009 - 0306 AHRQ AAA_provider F.indd What should I know about AAA? … What should I do with AAA screening test results? … harms from screening for AAA? … Screening for AAA does not reduce all-cause mortality. … What is the screening test for AAA?

12. Final Research Plan: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/abdominal-aortic-aneurysm-screening
    November 30, 2017 - What are the effects of rescreening for AAA on health outcomes or AAA incidence in a previously screened … , asymptomatic population without AAA on initial screening? … Do the effects of rescreening for AAA vary by the time interval between screenings? … What are the harms of one-time and repeated screening for AAA? … Are there externally validated risk models for screening for AAA?   

13. Archived: Cost-Effectiveness Analyses of Population-Based Screening for Abdominal Aortic Aneurysm: Evidence Synthesis: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/cost-effectiveness-analyses-of-population-based-screening-for-abdominal-aortic-aneurysm-evidence-synthesis/abdominal-aortic-aneurysm-screening-february-2005
    February 15, 2005 - The USPSTF used this review to prioritize AAA screening as a topic requiring an update. … asymptomatic adults for AAA. … size motivating treatment, prevalence of AAA, AAA-specific mortality, operative mortality rates (elective … Effects Are all important drivers of effectiveness included—e.g., AAA prevalence, AAA rupture rates … s (age 50 vs 70), and has a much lower AAA prevalence than Lee et al.'

14. Archived: Evidence Summary: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary8/abdominal-aortic-aneurysm-screening-2014
    January 15, 2014 - screening in men aged 65 years or older reduced AAA rupture and AAA-related mortality rates for up to … decreased AAA rupture and AAA-related mortality rates but had little or no effect on all-cause mortality … The primary trial outcome was AAA-specific mortality (defined as all AAA deaths plus all deaths within … 30 days of AAA surgical repair). … may reduce AAA-specific and all-cause mortality, as well as AAA rupture rates.

15. Archived: Abdominal Aortic Aneurysm: Screening, 1996 | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening-1996
    January 01, 1996 - reached a hospital and survived surgery. 2 The large majority of deaths from AAA occur in older men … and women men over 60 and women over 70 accounted for 95% of all deaths from AAA in a recent report. … The pathogenesis of aneurysms is not completely understood, but well-established risk factors for AAA … The accuracy of physical examination in detecting AAA is not completely known. … , or smoking) are at highest risk for AAA and death due to ruptured aneurysms.

16. Evidence Summary: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/abdominal-aortic-aneurysm-screening
    December 10, 2019 - Main Outcomes and Measures: AAA and all-cause mortality; AAA rupture; treatment complications. … , the effects of rescreening for AAA on health outcomes or AAA incidence (KQ2), and the effectiveness … When assessing the benefits of repeated AAA screening and the harms of screening for AAA, RCTs and large … All trials defined AAA as an aortic diameter of 3.0 cm or greater, and AAA prevalence varied from 4% … What are the effects of rescreening for AAA on health outcomes or AAA incidence in a previously screened

17. Primary Care Screening for Abdominal Aortic Aneurysm: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/XAaYbGVD_xRoMfQ-huJkJq
    December 10, 2019 - cm) AAA treatment benefits and harms. … MAIN OUTCOMES AND MEASURES AAA and all-cause mortality; AAA rupture; treatment complications. … , the ef- fects of rescreening for AAA on health outcomes or AAA incidence (KQ2), and the effectiveness … When assessing the benefits of re- peated AAA screening and the harms of screening for AAA, RCTs and … All trials defined AAA as an aortic diameter of 3.0 cm or greater, and AAA prevalence varied from 4%

18. Archived: Evidence Summary: Aspirin Use to Prevent Cancer: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - , BMD, ETDRS, JPAD, POPADAD, TPT ǁ BMD, TPT ǁ AAA, BMD, JPAD, TPT ǁ , POPADAD AAA, BMD, ETDRS, … AAA = Aspirin for Asymptomatic Atherosclerosis; ABI = ankle–brachial index; BMD = British Male Doctors … , BMD * , HOT, POPADAD, PPP Primary ≥4 y Any 4 49,641 0.98 (0.92–1.05) AAA, BMD * , … POPADAD, WHS Primary ≥4 y Daily 3 9765 0.88 (0.75–1.02) AAA, BMD * , POPADAD … ≥1 y ≤100 mg/d 5 67,787 0.98 (0.93–1.04) AAA, HOT, POPADAD, PPP, WHS Rothwell 2012

19. Aspirin for the Prevention of Cancer Incidence and Mortality: Systematic Evidence Reviews for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/Njxn2r3qtWKdBf2_VhS2Aw
    April 01, 2016 - CRC cases, 240 CRC deaths k = 2; n = 7588; 216 incident CRC cases Primary CVD prevention studies AAA … , BMD, ETDRS, JPAD, POPADAD, TPT�� BMD, TPT�� AAA, BMD, JPAD, TPT��, POPADAD AAA, BMD, ETDRS, HOT, … et al, 1988 (BMD) (54) Belch et al, 2008 (POPADAD) (55) MRC, 1998 (TPT) (52) Fowkes et al, 2010 (AAA … AAA = Aspirin for Asymptomatic Atherosclerosis; ABI = ankle–brachial index; BMD = British Male Doctors … (0.74–0.99) AAA, BMD*, POPADAD (SAPAT) Primary ≥1 y ≤325 mg/d 5 67 787 0.98 (0.93–1.04) AAA, HOT, POPADAD

20. Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/j69Hq5ALvzg74e-ngkzSep
    April 01, 2016 - Year (Reference) HOT, 1998 (24) JPAD, 2008 (25) PHS, 1989 (26) BMD, 1988 (27) TPT, 1998 (29) AAA … al (main analysis), 2015 (5)* Any 7 94 307 1.59 (1.32–1.91); I2 = 22.2% HOT, JPAD, PHS, BMD, TPT, AAA … , WHS ≤100 mg 5 67 097 1.58 (1.29–1.95); I2 = 28.6% HOT, JPAD, TPT, AAA, WHS ATT Collaboration, 2009 … ), 2015 (5) Any 10 114 540 1.34 (1.07–1.70); I2 = 0% PPP, TPT, HOT, JPAD, PHS, JPPP, BMD, POPADAD, AAA … , and WHS ≤100 mg 8 87 330 1.30 (1.00–1.68); I2 = 0% PPP, TPT, HOT, JPAD, JPPP, POPADAD, AAA, and WHS