-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-protocol.pdf
April 19, 2023 - A Supplemental Evidence And Data for Systematic review (SEADS) portal will be available
and a Federal … appropriateness of pooling data.19 We will synthesize data
using a Hartung, Knapp, Sidik, and Jonkman … For CQs, we will use a thematic approach, noting the principles and domains of the models
and then cross-walking … Based on these factors, the overall strength of evidence for each intervention/comparator/
outcome will … Childhood maltreatment predicts unfavorable course of illness
and treatment outcome in depression: a
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
May 14, 2010 - , and additional data on the efficacy of existing agents (zoledronic
acid; calcium and vitamin D) have … of the use of pamidronate with deterioration of renal function.7,8 Based on these
findings, AHRQ commissioned … criteria and will go on to data abstraction. … The data relevant to each outcome will be presented in individual tables. … On some specific reports such as reports requested by the Office
of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - Data Synthesis
After data extraction, we determined the feasibility of
completing a quantitative synthesis … in use, and clinical relevance and timing
of the outcome measures. … There are few
available data on patient preferences relevant to the use
of OCs as primary prevention … Better data on the relative
quality-of-life effects of regular OC use, and the outcomes
we reviewed … The effects of OC use on colorectal and breast cancer
incidence were a major contributor to the overall
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
December 30, 2015 - We did not assess
strength of evidence on this data. … a quantitative tallying of criteria, or a
judgment on the part of the reviewers. … Revised text: ‘Based on these factors, the overall
strength of evidence for each outcome was judged … a quantitative tallying of criteria, or a
judgment on the part of the reviewers. … It relies on past
systematic reviews and a new data extraction from the
published literature.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_disposition-comments.pdf
May 19, 2013 - of presentation
of data and outcome measures and (c) testing
interventions that target high risk groups … Magnitude is listed on the data tables
but is not always discussed. … There is a significant amount of data given the
number of interventions and outcomes being
assessed … useful (e.g., based on a given outcome of
interest, stakeholders can see the range of
interventions … available and their impact on that
outcome).
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
January 01, 2012 - For example, consider an epidemiologic study of
the effect of treatment A (exposed) on outcome Y. … treatment and, importantly, have no
effect on the outcome of interest (supported by
available evidence … For example,
in a study assessing the risk of cancer in statin
use,4 users of glaucoma drugs (like … may provide detailed data on the use of drugs,
biologics, and devices and on the severity of
underlying … When there is a dose effect on
the outcome of interest, the dose of the exposure
and comparison drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - common data
definitions, and the use of patient identifiers. … purposes and the intended use
of the data. … Determining whether the registry should use a case
report form to collect AEs should be based on the … and outcomes on the
association between the a priori exposure of interest and the outcome(s) … The practice of making inferences about causation largely on the outcome of tests of
statistical significance
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
June 12, 2012 - Guidelines have been published by the American Academy of Neurology on the use of
pharmacologic agents … , population, number of subjects, research methods, and outcomes.35
We will also collect data on … Each key outcome on each comparison of interest will be given an overall
evidence grade based on the … data
Described the completeness of outcome data for
each main outcome, including attrition and
exclusions … In an aggregated form such as a table, data
from the original studies should be provided on the
participants
-
digital.ahrq.gov/sites/default/files/docs/citation/r21hs023641-levin-final-report-2018.pdf
January 01, 2018 - official views of the Agency for Healthcare Research and Quality. … based on user feedback and outcomes data monitoring. … The implementation of e-triage did represent a major change
from heavy reliance on subjective assessment … some meaningful
concepts at a research intersection that will progress; use of integrated EHR systems … the risks of supporting self-fulfilling processes, will be the on-going science and art of machine
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
December 11, 2018 - research needs on pain. … The recent
publication of evidence-based guidelines on opioid use for chronic pain by the Centers
for … Disease Control (CDC),12 which includes a recommendation on the preferred use of
non-opioid treatment … from the published results of a study, or if we are aware of
unpublished data, we will query the authors … • Precision: describes the level of certainty of the estimate of effect for a
particular outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
November 24, 2014 - A
review looking at use of PK/PD on clinical outcomes in a
broader range of infections (e.g., treatment … Unfortunately though the included studies
reported on a wide variety of pathogens, their outcomes data … There was a lack of data to support the use of continuous
infusion of betalactam antibiotics compared … of studies would ever be competitive for
federal funding given other research priorities). … Helps
readers clearly understand the lack of data to support the
use of PK/PD measures in guiding antibiotic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-cough_research-protocol.pdf
October 22, 2012 - Data Abstraction and Data Management
The research team will create data abstraction forms for the KQs … The grading will be outcome specific such that a given study that analyzes its primary
outcome well … We will use a checklist to guide the assessment of
applicability. … We will use these data to evaluate the applicability to clinical practice, paying
special attention … in use, and clinical relevance and timing of the outcome
measures.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
February 01, 2012 - Question Development and Research Design Considerations .................................... 9
Results … of reaching relative consensus on research
priorities in this broad and complex topic area. … A total of 22 studies provided data on a variety of short- and long-term
outcomes for patients with … Research Question Development and Research Design
Considerations
Using guidance from a draft AHRQ … of reaching relative consensus on research
priorities in this broad and complex topic area.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
July 10, 2023 - In practice, a clinical
diagnosis of GSM is usually made based on the presence of symptoms in a post … , such as women with a history of
breast cancer, has relied on expert consensus in the absence of robust … appropriateness of pooling data.24 We will synthesize data using a Hartung, Knapp,
Sidik, and Jonkman … Impact of vulvovaginal health on postmenopausal women: a
review of surveys on symptoms of vulvovaginal … The Use of Vaginal Estrogen in Women With a History of Estrogen-
Dependent Breast Cancer.
-
cdsic.ahrq.gov/sites/default/files/2023-09/Stakeholder%20Center%202023%20Q3%20Report%20to%20AHRQ%209.27.23.pdf
January 01, 2023 - The product also documents challenges related to the capture or use of preference data and
outlines … As such,
it reports on the current state of content adoption and use of data standards for collecting … routine collection and use of preference data through the targeted research agenda and action plan … The list of
gaps and recommendations may serve as an action plan for the research community to use in … current use of data standards for
collecting and using patient preference data.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - We acknowledge that
both types of reporting bias are difficult to reliably detect
on the basis of data … One hundred and thirty-one study groups reported the
use of a single form of imaging guidance (83 stereotactic … of data. … Because delayed diagnosis on the basis of biopsy results
is the most important (adverse) outcome related … The next focus of research should be biopsy under
MRI guidance, which is a new technique that is likely
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
April 25, 2013 - While we agree that funding issues may preclude
addressing some of the stated research priorities, we … We have added points to the research gaps section:
- Further development of data on the use of echo … outcome data, or data on mortality. … outcome data, or data on mortality. … The research gaps could use some refining.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_executive.pdf
January 01, 2014 - Despite these recent data, a number
of questions remain about the use of antiplatelet and
anticoagulant … • With planned GPI use, bivalirudin reduced the rate of
the composite outcome of all-cause mortality … There was a paucity of data on the optimal timing of
oral antiplatelet agents as initial treatment for … of use of these
agents based on the type of stent used during PCI. … The final research gap for KQ 3 is the limited and
inconsistent data on long-term anticoagulant therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicide-prevention_disposition-comments.pdf
October 04, 2016 - on a national level, even for
routine sharing of clinical data; the lack of
adequate access to data … But I think its essential to clarify
that selection of the right source depends on the outcome
of interest … , (3)
familiarity of the research team experts
with the data systems of those states. … The legal feasibility of
linkage depends on the applicability to the
specific purpose of the data linkage … They also did a good job interpreting the data in
the context of current challenges to research and
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/postpartum-care-one-year-protocol-amendment.pdf
April 25, 2022 - We typically use a threshold for the prediction score of the unscreened citations of 0.40 (this
threshold … /care providers, objective outcome assessors, and subjective outcome assessors; incomplete
outcome data … We will also use
items from the NHLBI Tool focusing on the adequacy of descriptions of study eligibility … , we will also use the items from the Cochrane Risk of Bias Tool16 that focus on issues
related to blinding … ; incomplete outcome data; selective outcome reporting; and other issues that
could be related to bias