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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary10/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
March 15, 2009 - previous USPSTF recommendation for the prophylactic use of aspirin to prevent CVD was based on data … With the availability of new data on benefits for women, the USPSTF decided to update its previous recommendation … by reevaluating the evidence for aspirin use in the primary prevention of CVD, with a focus on sex-specific … Data Sources and Searches
For evidence on the benefits of aspirin for the primary prevention … Further research is needed to establish the benefit of aspirin use in diabetic patients for the primary
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-children-and-adolescents-screening-june-2017
June 20, 2017 - The clinical significance of the small benefit of medication use is unclear. … of 0.12 (SD, 0.2) with the use of orlistat compared with a reduction of 0.06 (SD, 0.2) in the placebo … How to access and process FDA drug approval packages for use in research. BMJ . 2013;347:f5992. … Outcome data from the LEAP (Live, Eat and Play) trial: a randomized controlled trial of a primary care … The dashed line indicates a relationship between an intermediate outcome and a health outcome that is
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-section-3-topic-work-plan-development
June 22, 2025 - Data on the incidence/prevalence, complications, morbidity, and mortality of the condition of interest … The fact that a preventive service has a proven effect on an intermediate outcome does not necessarily … in the analytic framework as an intermediate outcome or a health outcome, depending on the specific … Review of Research Plan
Based on the full draft work plan, a draft research plan that contains the … The final approved research plan, including a section on Response to Public Comment, is posted on the
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/R3y9LSud52CGL8mG4wvxoT
June 09, 2020 - A dashed line indicates a health outcome that
immediately follows an intermediate outcome. … Research and
Quality methods guidance, based on the number, quality, and size of
studies and the consistency … Data on effects of psychosocial interventions on other health,
social, and legal outcomes were limited … Based on the range in test accuracy estimates and a preva-
lence of drug use among adults of 11%,3 the … for the integrity of the data and the
accuracy of the data analysis.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Yc24U4wMLXGoqE5NjwRVA6
April 17, 2018 - The strength of evidence for each outcome was assessed based
on the Agency for Healthcare Research and … A dashed line is used to
reflect the natural progression of
disease between an intermediate
outcome and … a health outcome. … a Calculated based on raw data provided in study; the authors reported an
age-adjusted RR of 0.78 (95% … for the integrity of the data and the
accuracy of the data analysis.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/drug-use-illicit-screening
June 09, 2020 - for Healthcare Research and Quality methods guidance, based on the number, quality, and size of studies … Data on effects of psychosocial interventions on other health, social, and legal outcomes were limited … Based on the range in test accuracy estimates and a prevalence of drug use among adults of 11%, 3 the … Validation of the Drug Abuse Screening Test (DAST-10): a study on illicit drug use among Chinese pregnant … A dashed line indicates a health outcome that immediately follows an intermediate outcome. a Screening
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary26/gestational-diabetes-screening-2008
May 15, 2008 - This report is based on research conducted by staff at the Agency for Healthcare Research and Quality … diabetes is increasing; thus, data on the risks and benefits of early gestational diabetes screening … Neonatal: Limited data in small studies found no harm to the fetus; we found no good-quality data on … The significance of one abnormal glucose tolerance test value on adverse outcome in pregnancy. … The impact of universal screening for gestational glucose intolerance on outcome of pregnancy.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
August 20, 2024 - National Institute on Minority Health and Health Disparities and the Office of Research on Women’s Health … Anemia and iron-deficiency anemia: compilation of data on pregnancy outcome. … A randomised placebo-controlled trial to determine the effect of iron supplementation on pregnancy outcome … reporting on methods for outcome assessment; unclear documentation of iron deficiency or use of supplementation … reporting on methods for outcome assessment; unclear documentation of iron deficiency or use of supplementation
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/_nVeFxDCT9L-_cnDf_V3fK
July 17, 2018 - moving down a risk category with a
cardiovascular disease outcome (known as the event NRI), plus the … For all KQs, additional de-
scriptive and outcome data are available in the full report. … in these outcomes, as the primary outcome of
this trial was a change in CVD risk factors and Framingham … A 2015 analysis of data from the MESA study91 found inconsis-
tent results. … Use of electron
beam tomography data to develop models for
prediction of hard coronary events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/56vB_8UTTE_HjygLvJfYqM
May 01, 2002 - Research and Quality or the U.S. … Screening for Depression in Adults
134
Outcome Absolute
Author, year, reference measured Outcome data … Screening for Depression in Adults
135
Outcome Absolute
Author, year, reference measured Outcome data … Research assistants screened patients on the day of a
regularly scheduled clinic visit and gave same-day … care: effect on clinical outcome.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/drug-use-illicit-screening
October 20, 2016 - The resulting Evidence Review will form the basis of the USPSTF Recommendation Statement on this topic … Within the screening piece of the framework, there is also a question related to the accuracy of drug … use) (i.e., change in drug use is not a stated aim but is a reported outcome)
Condition
Use of … the basis of drug use or a related behavior or condition
KQs 4, 5: Studies in which at least 50% … draft research plan was posted on the USPSTF Web site for public comment from August 4 to August 31,
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/unhealthy-alcohol-use-adolescents-adults-behavioral-counseling-interventions
May 16, 2024 - What are the harms of screening for unhealthy alcohol use in adolescents and adults? 4. a. … in alcohol use is not a stated aim, even if it is a reported outcome
Condition
Unhealthy alcohol … the basis of alcohol use or a related behavior or condition
KQs 4, 5: Studies in which at least 50% … a primary aim of the study. … draft Research Plan was posted for public comment on the U.S.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Qpv8h6ZMbYLYzakVrNQoj2
October 11, 2022 - demonstrate an effect on the primary outcome of suicidal ideation;
as a result, findings by chance or … for use in
screening for depression by the American Academy of Pediatrics.76
One study of the accuracy … The consequences of a
false-negative would largely depend on the severity of the missed
diagnosis; the … the data in the study and takes
responsibility for the integrity of the data and the
accuracy of the … of the data; or preparation, review, or
approval of the manuscript findings.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/SEcYfGZqGdoqdd8j4CCVuy
May 01, 2008 - Maternal: Limited data are mixed on whether anxiety/quality of life is
worsened in the first several … Neonatal: Limited data in small studies found no harm to the fetus; we
found no good-quality data on … diabetes is increasing; thus,
data on the risks and benefits of early gestational diabetes
screening … The significance of one abnormal glucose tolerance test value on adverse outcome in pregnancy. … The impact of universal screening for gestational glucose intolerance on outcome of pregnancy.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6L2obA88s86MoZDbWtMPTU
December 01, 2011 - Eight of the
RCTs reported an outcome of fracture at any site, 5 re-
ported data on hip fracture, 2 reported … For the female breast cancer outcome, 1 poor-quality
study (of 142 cases) provided insufficient data … The strengths and limitations of meta-analyses
based on aggregate data. … 0 20 40 60 80 100
Authors Specified a Primary
Outcome of the Study
Prospective Collection of Data … Outcome of the Study
Prospective Collection of Data
<20% Loss to Follow-up
Clear Definition of Outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/other-supporting-document19468/tobacco-and-nicotine-use-prevention-in-children-and-adolescents-primary-care-interventions
April 28, 2020 - Data Extraction and Synthesis: One investigator abstracted data and a second investigator checked data … of the intervention, role of primary care, and definition of smoking outcome) on tobacco use. … , role of primary care, or definition of smoking outcome and effects on smoking cessation. … The influence of a family program on adolescent tobacco and alcohol use. … A dashed line indicates a health outcome that immediately follows an intermediate outcome.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/unhealthy-alcohol-use-in-adolescents-and-adults-screening-and-behavioral-counseling-interventions
October 20, 2016 - The resulting Evidence Review will form the basis of the USPSTF Recommendation Statement on this topic … use is not a stated aim, even if it is a reported outcome)
Condition
Unhealthy alcohol use * … the basis of alcohol use or a related behavior or condition
KQs 4, 5: Studies in which at least … draft research plan was posted on the USPSTF Web site for public comment from August 25 to September … Suggestions for implementation of the review (e.g., stratifying analyses based on alcohol use severity
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www.uspreventiveservicestaskforce.org/Home/GetFile/1/588/gdart/pdf
May 01, 2008 - Maternal: Limited data are mixed on whether anxiety/quality of life is
worsened in the first several … Neonatal: Limited data in small studies found no harm to the fetus; we
found no good-quality data on … diabetes is increasing; thus,
data on the risks and benefits of early gestational diabetes
screening … The significance of one abnormal glucose tolerance test value on adverse outcome in pregnancy. … The impact of universal screening for gestational glucose intolerance on outcome of pregnancy.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/b5LjDb3-UoPV8LEWavJWB8
February 01, 2010 - We found no
data on maintenance of treatment ef-
fect or safety after the 6 to 12 months
of active treatment … the
majority of the trials did use a common
metric. … Out-
come data from the LEAP (Live, Eat and Play)
trial: a randomized controlled trial of a pri-
mary … A randomized trial of the effects of reducing
television viewing and computer use on
body mass index … curves.61 BMI SDS requires the use of
published computer programs that ac-
cess reference data and formulae
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/statin-use-in-adults-preventive-medication
August 23, 2022 - The likelihood that a patient will benefit from statin use depends on their absolute risk of having a … height in meters], or hemoglobin A1c level >6%). 21
Current Practice
Data on statin use for the … In several trials, primary outcome was reported as a composite of CVD events, with the exact components … cataract surgery, which was unanticipated and not a predetermined outcome of the trial (3.8% vs 3.1% … The USPSTF understands these concerns and calls for more research on improving the accuracy of CVD risk