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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/latent-tuberculosis-infection-screening
June 17, 2021 - They should not be construed as an official position of the Agency for Healthcare Research and Quality … Research Approach
The Research … use of chemotherapy. … underlying illness or use of medications, injection drug use, or radiographic evidence of prior healed … draft Research Plan was posted on the USPSTF website for public comment from March 11 to April 7, 2021
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - Detailed methods and secondary outcome analyses are available in our full report. 18
Data Sources and … data into standardized evidence tables, and a second checked data accuracy. … Data Synthesis and Analysis
We examined 4 primary beneficial outcomes based on a priori decisions and … In a priori subgroup analysis, the WHS showed that the beneficial effect of aspirin on total stroke ( … Steering Committee of the Physicians' Health Study Research Group.
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www.uspreventiveservicestaskforce.org/uspstf/document/other-supporting-document19727/drug-use-illicit-primary-care-interventions-for-children-and-adolescents
September 03, 2020 - addressed illicit drug use and the study reported a drug use outcome. … A second reviewer checked the data for accuracy. … on the reduction of use in those who were regular users, hazardous users, or who had a likely substance … of the data; and preparation, review, or approval of the manuscript findings. … Effectiveness of the “Healthy School and Drugs” prevention programme on adolescents’ substance use: a
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary26/tobacco-use-in-children-and-adolescents-primary-care-interventions-2013
December 11, 2012 - Although all of the combined trials relied on self-reported smoking as the primary outcome, they used … The definition of what constituted a smoker at baseline and the primary outcome measure differed among … * Calculated on the basis of data requested from the author. … † Calculated on the basis of presented data.
‡ Not included in the meta-analysis. … The influence of a family program on adolescent tobacco and alcohol use.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication-september-2014
September 09, 2014 - Research Needs and Gaps
Research is needed on the effect of low-dose aspirin on the development … Eleven RCTs (23,332 women) reported on the outcome of placental abruption (6 trials in women with increased … Eighteen trials reported on the outcome of perinatal mortality (with 4 smaller studies reporting no events … Five trials (1 good-quality) in a total of 2748 women reported on the outcome of blood loss. … The USPSTF added language on the timing of initiation of low-dose aspirin in the Research Needs and Gaps
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-section-4-evidence-review-development
June 22, 2025 - been the focus of recent research activity or topics with limited existing research and shorter time … or by type of intervention/comparison or outcome, depending on how the Task Force has conceptualized … and average outcome within a population. … Finally, some ecological studies use data collected in ways that are not accurate or reliable. … When a condition is a common cause of mortality, all-cause mortality is the desirable health outcome
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/wBcZfBcVp8N3-cyT3Peysv
April 01, 2016 - Data Synthesis and Analysis
We examined 4 primary beneficial outcomes based
on a priori decisions and … In a
priori subgroup analysis, the WHS showed that the
beneficial effect of aspirin on total stroke ( … Absolute Risk Reduction With Low-Dose Aspirin Use ≤10 Years
Outcome Risk Level* Baseline Risk for Outcome … -
sistent evidence of subpopulation differences in aspirin
use was an enhanced effect on MI in older … A more recent analy-
sis, however, found that use of the pooled cohort equa-
tions (as part of the American
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/myqvgr-dsW7k3eQbwj4aR4
February 01, 2013 - Although all of the combined trials relied on self-
reported smoking as the primary outcome, they used … The definition of what constituted a smoker at base-
line and the primary outcome measure differed among … Soh accepted a position at the Pharmaceutical Research
and Manufacturers of America during the finalization … The influence of a family program on adolescent tobacco and alcohol use. … the basis of data requested from the author.
† Calculated on the basis of presented data.
‡ Not included
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/oaVhMNVAnx3b5-UUunZkjr
December 17, 2018 - A second reviewer checked the data for accu-
racy. … cused on the reduction of use in those who were regular users,
hazardous users, or who had a likely substance … for the integrity of the data and the
accuracy of the data analysis. … of the data; and preparation, review,
or approval of the manuscript findings. … Effectiveness of the “Healthy School and Drugs”
prevention programme on adolescents’ substance
use: a
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-bleeding-risks-with-aspirin-use/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - outcome, we calculated a range of expected event rates after aspirin intervention using the pooled relative … prevention trials ( Table 1 ). 15 In cohort data, the effect of aspirin on hospitalizations for major … on the studies included and whether the outcome included any cases of intracranial hemorrhage. 3 , … Although studies varied in the duration of aspirin use and data were sparse and somewhat mixed on whether … The use of aspirin for primary prevention of colorectal cancer: a systematic review prepared for the
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/j69Hq5ALvzg74e-ngkzSep
April 01, 2016 - outcome, we calcu-
lated a range of expected event rates after aspirin in-
tervention using the pooled … In cohort data, the effect of aspirin on hospitaliza-
tions for major GI bleeding events was similar … on the studies in-
cluded and whether the outcome included any cases of
intracranial hemorrhage (3, … Although studies varied in the
duration of aspirin use and data were sparse and some-
what mixed on whether … The use of aspirin for
primary prevention of colorectal cancer: a systematic review pre-
pared for the
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/aspirin-to-prevent-cardiovascular-disease-preventive-medication
April 26, 2022 - of follow-up, duration of use, and timing of outcome measurement (eFigure 1 in the JAMA Supplement … use, timing of outcome measurements, and length of follow-up. … Use of a marginal structural model to determine the effect of aspirin on cardiovascular mortality in … Effect of low-dose aspirin on functional outcome from cerebral vascular events in women. … Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/alcohol-misuse-screening-and-counseling-2004
April 06, 2004 - Research and Quality (AHRQ) under a contract to support the work of the USPSTF. … As a result of the emphasis of the last USPSTF recommendations on alcohol-related screening, and the … involved; the use of usual care or other clinical or research personnel; components of the intervention … The Alcohol Use Disorders Identification Test (AUDIT): a review of recent research. … Truth or consequences: the validity of self-report data in health services research on addictions.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/y6xRBv7uSZY5bGCx7y48x7
May 01, 2009 - Preventive Services Task Force (USPSTF) last
issued a recommendation on the use of folic acid in women … We excluded studies that did not
include new evidence since the 1996 review; did not report
outcome data … The fourth study was a meta-analysis of studies on
pre- and periconceptional multivitamin use and congenital … Use of folic acid and delivery outcome: a prospec-
tive registry study. … This was a study of dose-response that
reexamined data from a study
reviewed in the 1996 USPSTF
report
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/behavioral-counseling-research-and-evidence-based-practice-recommendations-us-preventive-services-task-force-perspectives
March 01, 2014 - between the type of outcome measure and the effect size. … Use of these metrics, along with better reporting of data on the number, frequency, and duration of intervention … measures of intake, including alcohol use. 33 In the mid-2000s, a workgroup convened by the Society … to failure to analyze and report results for all of the data collected during a clinical trial. … A Framework to Facilitate the Use of Systematic Reviews and Meta-Analyses in the Design of Primary Research
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-xii-summary-evidence-table-evidence-reviews
July 01, 2017 - , specific medications), depending on the topic. … for that key question, particularly when the stratified data may be the basis for considering a subpopulation-specific … Imprecise results may suggest the need for further research. … Within the appropriate level of stratification, a combined summary of individual study (or outcome-specific … for each stratum for internal use by the USPSTF in its independent process of assessing the evidence
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
January 10, 2017 - Studies were included if they focused on the use of folic acid supplementation for the prevention of … ) for any use in the 3 months before conception. 20
One case-control study from a limited data source … Limitations of the evidence relate to insufficient data and the quality of evidence as a whole. … a Reasons for exclusion: Wrong publication type/not original research: study was not original research … timing, 20 , 21 1 new study (postfortification) shows a protective effect of use before pregnancy on
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4zmYnqJXLv8g4LzLrrDDrm
December 01, 2014 - OTHER CONSIDERATIONS
Research Needs and Gaps
Research is needed on the effect of low-dose aspirin on … Research on how
Table. … Eighteen trials reported on the outcome of perinatal
mortality (with 4 smaller studies reporting no events … Five trials (1 good-quality) in a total of
2748 women reported on the outcome of blood loss. … The USPSTF added language on the timing of
initiation of low-dose aspirin in the Research Needs and
Gaps
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/z8AVsCHJEZUBSJtdSx424H
May 23, 2019 - Six of these trials (50–53, 55, 57) reported a signifi-
cant effect on at least 1 drinking outcome (Table … The Alcohol Use Disorders Identification Test
(AUDIT): a review of recent research. … Truth or consequences: the validity of self-report data
in health services research on addictions. … As a result of the emphasis of the last USPSTF recommen-
dations on alcohol-related screening, and the … types involved; the use of usual care or
other clinical or research personnel; components of the interven
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary51/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication-september-2014
April 08, 2014 - , 0.76 to 0.98]; I 2 = 33.2%) in a meta-analysis of 10 trials with the outcome (11,779 participants … Absolute risk reductions were calculated on the basis of event rates in the trial data at 25th- and 75th-percentile … Comparisons of dosage effects when a cut point of 75 mg was used revealed only 1 outcome with a significant … data, but information on long-term harms is sparse. … Maternal obstetric outcome measures in a randomised controlled study of labetalol in the treatment of