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Showing results for "a research on the use of outcome data".

81. Ced-Appendix-3 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
    June 24, 2022 - Pearson Question Frame the question, which may involve use of a PICOTS framework Pearson Data Curate … and outcome of interest when conducting a study using RWD NAM 2018 Validating data as a crucial step … specific data elements that should be captured by a registry depend on the sponsor’s intended use or … data” provides a more complete picture of a medical products NICE_cancer Data_source Use data from … definition FDA2021 Design_outcomes Define an outcome of interest based on the clinical, biological,

82. Public-Reporting-Quality-Improvement Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
    August 17, 2011 - A recent Agency for Healthcare Research and Quality (AHRQ) series on best practices in public reporting … Previous research has examined the effect of public reporting on quality at several levels (e.g., health … the ultimate outcome of interest. … Studies in which the data are available to a limited number of stakeholders or to a certain type of … Differences will be resolved by discussion and the use of a third rater.

83. Research Protocol: Clostridium difficile Infection Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
    December 23, 2014 - Use of the term CDI indicates the major focus of this review is on the presence of clinical disease, … , we may use their abstracted individual study, population, and outcome data, which will be verified … of participants and personnel, blinding of outcome assessment, incomplete outcome data (i.e., was incomplete … Based on these factors, the overall strength of evidence for each outcome will be rated as.40 • High … Are statistical methods used to assess the primary outcome appropriate to the data?

84. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - Types of Missing Data When considering the potential impact of the missing data on the registry findings … On the other hand, consider a study in which missingness in the outcome differs only by level of a confounder … Z: individuals with Z=1 have a 20 percent chance of having a missing value for the outcome, while those … missing data on a set of selected covariates. … a measurement of outcome.

85. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_disposition-comments.pdf
    October 05, 2010 - The following statement describes the use of clinical examination in determining the presence of an … post-hoc decision was made to extract data on this outcome in the studies that had been included in … In other words, a study with cuff integrity data had to report on one of the other 6 outcomes in order … The needs for future research need clarification; it is critical to use patient-rated measures, with … Discussion [The section on future research provides sound advice on general principles of study design

86. Acs-Pci-Adjunctive-Devices Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
    July 01, 2010 - Data Abstraction and Data Management Two reviewers will use a standardized data-abstraction tool … Further research may change our confidence in the estimate of effect and may change the estimate. … We will assess whether or not the effect sizes were on the same side of unity; whether the range of … to a given outcome. … On some specific reports such as reports requested by the Office of Medical Applications of Research

87. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amended.pdf
    September 25, 2024 - , deviations from intended interventions, missing outcome data, measurement of the outcome, and selection … Our decision to conduct a quantitative synthesis depends on the number of studies, population, research … If the data permit, we plan to conduct a network meta-analysis (NMA), specifically focusing on the component … We will assign a rating of Insufficient when the evidence does not permit a conclusion for the outcome … Research Review: The effects of mindfulness- based interventions on cognition and mental health in children

88. Abnormal-Uterine-Bleeding Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
    November 21, 2011 - that provide sufficient detail regarding methods and results to enable use and adjustment of the data … measure for an outcome listed in the PICOTS  Relevant outcomes must be extractable from data presented … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … Based on a preliminary review of the literature and input from experts during the topic refinement … conducting a systematic review of harms data. 43 As a meta-analysis is not likely to be feasible

89. Renal-Function Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
    June 13, 2013 - The Key Questions The Key Questions were posted on the Agency for Healthcare Research and Quality’s … Data Abstraction and Data Management We will use a systematic approach to extract all data to minimize … A third reviewer will audit a random sample of articles to ensure consistency in the data abstraction … For Key Questions 1, 2, and 3, we will collect information on how the ACS outcome was defined in the … We will collect data on subgroups of interest, including gender, age, ethnicity, stage of kidney disease

90. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure_research-protocol.pdf
    April 11, 2011 - o Not just as a device to measure the outcome BP. … The grading will be outcome-specific such that a given study that reports its primary outcome well but … did an incomplete analysis of a secondary outcome would be graded of different quality for the two … For each outcome (or set of outcomes), we will assign a grade for the strength of evidence: high, moderate … On some specific reports such as reports requested by the Office of Medical Applications of Research

91. FRN 41 - Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
    February 01, 2013 - Question Development and Research Design Considerations ...........................13 Results .... … to allocate to any of the 19 research priorities, with a maximum of 3 votes per item. … Research Question Development and Research Design Considerations For the top-tier Future Research … on variables and outcome of interest --Duration of follow-up No Observational Study: New Data … needed for outcome --Availability of data --Consistency of data reporting on variables and outcome

92. Methods Guide for Comparative Effectiveness Reviews - Expanded Guidance on Selected Quantitative Synthesis Topics (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - Although the use of a composite outcome as the primary outcome in a clinical trial can reduce sample … When a meta-analysis of a composite outcome is undertaken, trials without data for all component outcomes … rates. 7 • Use a simple weighted regression of the effect size on the control rate to rule out … in a meta-analysis based on the scope of the research question. … in a meta-analysis based on the scope of the research question.

93. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amendment.pdf
    February 05, 2025 - , deviations from intended interventions, missing outcome data, measurement of the outcome, and selection … Our decision to conduct a quantitative synthesis depends on the number of studies, population, research … If the data permit, we plan to conduct a network meta-analysis (NMA), specifically focusing on the component … We will assign a rating of Insufficient when the evidence does not permit a conclusion for the outcome … Research Review: The effects of mindfulness- based interventions on cognition and mental health in children

94. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
    January 01, 2009 - the evaluation of genetic tests 3 is a model process for evaluating data on emerging genetic … on the process of care and patient outcome. … We present below a few critical thoughts on their use as phases in the assessment of tests. … to conduct a randomized trial to document the benefits of testing on patient outcome. … ACCE: A Model Process for Evaluating Data on Emerging Genetic Tests.

95. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
    January 01, 2009 - the evaluation of genetic tests 3 is a model process for evaluating data on emerging genetic … on the process of care and patient outcome. … We present below a few critical thoughts on their use as phases in the assessment of tests. … to conduct a randomized trial to document the benefits of testing on patient outcome. … ACCE: A Model Process for Evaluating Data on Emerging Genetic Tests.

96. Transparency of Reporting Requirements: Tympanostomy Tubes (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
    September 02, 2016 - Arguably the best way to obtain empirical data on the prevalence and impact of information bias (and … Methods Overview We will use a systematic review that is currently being conducted by our EPC on … Terminology We use the term study to refer to the conducted research. … Outcome reporting in industry-sponsored trials of gabapentin for off-label use. … Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research.

97. Mrsa-Screening-2010 Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
    January 01, 2010 - However, a recent report found that despite the use of an electronic flag denoting the need for isolation … O Did the analysis of outcome data incorporate a method for handling confounders such as statistical … for Healthcare Research and Quality for its Methods Guide,33,38 based on a system developed by the … Impact of alcohol hand-rub use on methicillin-resistant Staphylococcus aureus: an analysis of the literature … relevant outcome only as a frequency without a denominator.

98. S13 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s13.pdf
    October 01, 2007 - variety of questions, they all deal with a common subject: the use and effects of pharmaceuticals. … the exposure and the outcome is modi- fied by a third variable such that the magnitude of the association … Outcome misclassification is also a substantial threat to the validity of the study. … claims data, will be a unique resource on a massive and stable population, valuable for the studies … CONCLUSIONS The goal of our research community is to optimize the use of pharmaceuticals by improving

99. Dementia-Agitation-Aggression Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
    November 13, 2014 - clinicians on their use could help reduce inappropriate use of antipsychotics in patients with dementia … We will use data provided by the systematic review to assess strength of evidence for results without … of participants and personnel, blinding of outcome assessment, incomplete outcome data (i.e., was incomplete … Based on these factors, the overall strength of evidence for each outcome will be rated as:41 • High … A protocol for a systematic review of research on managing behavioural and psychological symptoms in

100. Ced-Topic-Refinement (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-topic-refinement.pdf
     November 01, 2022 - regulatory use of evidence from the Margolis Center for Health Policy Research at Duke University.33 … G Protocol A protocol describing the data source(s), key outcome(s), and key elements of design, at … A protocol describing the data source(s), key outcome(s), and key elements of design, at a minimum, is … A protocol describing the data source(s), key outcome(s), and key elements of design, at a minimum, is … on use of data generated in the usual care of patients may help assure the inclusion of a population