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effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
February 22, 2012 - tumor and to maximize the likelihood of a favorable therapeutic outcome. … )
○ Use of an independent outcome assessor
Additional elements are described below under Assessment … based on a selection of items proposed by Deeks and colleagues32 to inform the
approach used by the … ○ Did the analysis of outcome data incorporate a method for handling confounders such as
statistical … • The quality of included single-arm intervention studies will be assessed based on a set of
study
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
January 01, 2015 - The figure illustrates how the use
of pharmacologic, nonpharmacologic, or multimodal
treatments may … Extracted data
included the relevant population, intervention, baseline,
and outcomes data on the adult … A third type
of study was a pooled analysis of individual patient data
from several RCTs to report … high risk of
bias20 presented data on MDD subgroup BPI average pain
severity scores. … The use of observational methods to examine existing
electronic health data (e.g., health plan, integrated
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
January 01, 2011 - applications
and implications, a summary of
ongoing research, and information on
future research needs … Data on the utilization of
these various devices are limited. … Case series
and reports provide the majority of data on off-label use
(n=109 patients) of potential neurothrombectomy … did not include the majority of the
highest quality data on neurothrombectomy devices
(including that … There remains a need for
further research on the topic, including randomized
controlled trials to determine
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - information is gathered regarding the availability of data and impact of included
interventions on … Data Abstraction and Data Management
The research team will create data abstraction forms for the … The grading will be outcome-specific such that a given study that analyzes its primary
outcome well … We will
use a checklist to guide the assessment of applicability. … Survey on Drug Use and
Health.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
April 01, 2015 - full report, to retrieve research on
interventions for PPH. … intervention on PPH management as
a primary or secondary aim; analytic models must indicate data analysis … , and baseline and outcome data on constructs
of interest. … intervention on any outcome is insufficient or moderate, as the
observational data are biased and … However, few studies clearly provided data
on the success of these procedures and surgeries as the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_executive.pdf
August 01, 2014 - Since the publication of the initial review in 2011, a
sizable body of research has been published, … KQ 7: What evidence supports the use of a specific
behavioral treatment approach in children under the … and outcome data on constructs
of interest. … on at least one outcome measure, but a lack of consistency
in the interventions studied and outcome … Research Gaps and Needs
Given the heterogeneity of the expression of ASD
across children, a critical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
January 01, 2024 - on the conformation of
double bond(s), cis (hydrogen atoms on the same side) or trans (opposite side … We typically use a threshold for the prediction score of
the unscreened citations of 0.40 (this threshold … of groups) and relevant concepts addressed
for RCTs (i.e., related to missing data, outcome measurement … study will be considered to be high risk of bias
● If there are concerns about missing data, outcome … The structure of the data synthesis (Results section) will depend in part on the characteristics
of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
February 01, 2018 - Reporting of harms data in RCTs: a systematic review of empirical assessments against the CONSORT harms … outcome, the occurrence of the outcome
is a failed event, not an adverse event. … In general, if the intervention is being used to reduce the occurrence of a final health outcome, the … of effect, the precision of estimates, the statistical significance of findings, and other data on the … Reporting of harms data in
RCTs: a systematic review of empirical assessments against the CONSORT
harms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
July 01, 2012 - data were addressed appropriately,
the validity of outcome measures, and conflict of interest. … Length of stay
was analyzed qualitatively because the data reported for
this outcome were often highly … These studies did not show a benefit for
NPPV on any outcome.
Table D. … These studies did
not show a benefit for NPPV on any outcome. … Effect of failed extubation on
the outcome of mechanical ventilation. Chest. 1997;112(1):186-92.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
November 07, 2012 - Again a bit more on how the data limitations
impacted results would have been useful. … It would be much easier (albeit longer) if each outcome were on a
separate line. … research gaps are well developed but again there is a heavy
reliance on the summary data in table 31 … I am
not sure of the answer to this question, but again a bit more on policy
and research solutions … for
obtaining the data and the needed research.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children_research-protocol.pdf
November 01, 2010 - Did the article report on a relevant outcome of interest? OR
4. … Did the article report on a relevant comparator of interest? OR
5. … • Did the analysis of outcome data incorporate a method for handling
confounders such as statistical … : Further research is likely to have an important impact on
our confidence in the estimate of effect … On some specific reports such as reports
requested by the Office of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
June 01, 2012 - to use as intermediate outcomes for assessing the impact of a test on clinical outcomes, and (2) consider … to the outcome of interest. … The accuracy outcome of interest depends on how the test is used in an algorithm and its mechanism of … The use of the test, such as for diagnosis versus prognosis, is a factor. … A review was conducted on the use of noninvasive imaging in addition to a standard workup after detection
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
June 01, 2012 - to use as intermediate outcomes for assessing the impact of a test on clinical outcomes, and (2) consider … to the outcome of interest. … The accuracy outcome of interest depends on how the test is used in an algorithm and its mechanism of … The use of the test, such as for diagnosis versus prognosis, is a factor. … A review was conducted on the use of noninvasive imaging in addition to a standard workup after detection
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
November 12, 2013 - We will also perform a focused search for more recent systematic reviews on the
topic and use their … the interventions and comparators of interest, analytic
details, and outcome data. … The grading will be outcome
specific, such that a given study that reports its primary outcome well … Of note, the material used to solicit input will not include any data on outcome
15 … “indirect”) on the basis of the use of
surrogate outcomes or the need for indirect comparisons (e.g.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - and inadequate handling or reporting of
outcome data. … , and pooled data
across efficacy outcome measures. … Conclusions
This report provides a comprehensive synthesis of the
evidence on the comparative effectiveness … In summary, data on the comparative effectiveness of
individual FGAs and SGAs precluded drawing firm … Committee on Standards
for Systematic Reviews of Comparative Effectiveness Research,
Board on Health
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
November 01, 2021 - , the lack of empirical data on executive function training and
executive function coaches, the general … limitations: The extent to which studies reporting on a particular outcome
are likely to be protected … or unknown
(in the case of a single study)
• Indirectness: Generally reflects whether the outcome … • Imprecision: Describes the level of certainty of the estimate of effect for a
particular outcome … The use of actigraphy in the
monitoring of sleep and activity in ADHD: A meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_executive.pdf
July 01, 2012 - The SOE is a summary
rating of the confidence in the estimate of effect for each
outcome that incorporates … In addition to
addressing the impact of PCMH on specific outcomes,
we encourage the expanded use of … We therefore describe a
series of research priorities in this report. … and, ideally, use a more
consistent set of outcome measures and nomenclature for
PCMH components and … Developing
a policy-relevant research agenda for the patient-centered
medical home: a focus on outcomes
-
effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
October 01, 2007 - services
research on the use and outcomes of prescription drugs. … To make more effective use of the considerable poten-
tial for research on pharmaceutical use and outcomes … clinical
and outcome data for beneficiaries will expand the potential
of research with these datasets … These data have the
potential to serve as the foundation for a powerful national
research database on … The quality of Medicaid data for HIV/AIDS
research: examination of a statewide data base.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
December 19, 2013 - groups); and gaps in research on
important scientific questions.21 Although guidelines on use of opioids … In patients with chronic pain, what is the effectiveness of use of risk prediction
instruments on outcomes … from the published results of a study, or if we are
aware of unpublished data, we will query the authors … The feasibility of a quantitative synthesis
will depend on the number and completeness of reported outcomes … Research gaps on use of opioids for chronic
noncancer pain: findings from a review of the
evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea_research.pdf
April 01, 2010 - It is a collaborative network of research centers that
support the rapid development of new scientific … As part of the Symposium on Developing a Framework to
Assess Cancer Quality Indicators for End-of-Life … No data on this measure’s use, validity testing, or clinical performance as an
assessment of care or … quality measures lack data on reliability, validity, and feasibility. … The
measure is an operationalized version of a quality
process or outcome that at a minimum has defined