-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
January 01, 2010 - A further limitation of these approaches—and, specifically,
the use of isolation precautions—is the … The Key Questions were then posted on the
Agency for Healthcare Research and Quality (AHRQ) Web
site … Data Extraction and Quality Assessment
Data were abstracted by a team of reviewers and fact-
checked … Limitations of the Evidence Base, Research Gaps,
and Future Research Opportunities
The available evidence … Future research on MRSA screening should use
design features and analytic strategies addressing secular
-
effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
May 01, 2020 - Table A summarizes the SOE for the use of
partograms. … Ideally, the definition
would be derived based on data from a large group
of women who were followed … on Safe Labor
(CSL) data, and the data are not informative
about optimal timing of augmentation. … • Encouragement of use of core outcome
sets, such as those developed as part of the
CROWN (Core Outcomes … Effect of early
amniotomy on the outcome of spontaneous labour:
a randomized controlled trial of pregnant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
September 07, 2012 - The grading is on quality of the data
as presented not the study as performed. … Use of castor oil as a placebo is a theoretical
concern due to its use as an induction agent. … This is a paper I would use to discuss the
appropriate use of 17OH in my role on a state Medicaid
committee … be very
helpful in synthesizing the vast amount of published data on the
topic. … But, the list of questions serves as a guide for
future research.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-disposition-comments.pdf
October 01, 2021 - We discussed
BIA-ALCL in the Background (as a
potential harm), in the Methods (as
an outcome of interest … We discussed BIA-ALCL in the
Background (as a potential harm),
in the Methods (as an outcome of
interest … Breast implant illness was not an a
priori outcome of interest in our
Protocol (based on discussions … priori outcome of interest in our
Protocol (based on discussions
with the Key Informants and
Technical … We have added the sparsity of
long-term outcome data as a
limitation in the Strengths and
Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
September 01, 2011 - The use of inconsistent definitions of TRD in the trials
and the absence of analyses considering the … effect of
the number of current treatment failures on outcomes
hindered interpretation of data, leading … to our use of a
tiered system for analyses. … The field needs a standard definition of TRD that
investigators should use in their clinical trials
research … At the time we started this
comparative effectiveness review, clinical trial data on
some of the developing
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_disposition-comments.pdf
March 21, 2013 - Medical Eligibility
Criteria for Contraceptive Use, 201 from CDC
MMWR as a source for harms data. … We relied
on Package Inserts as the standard source of
regulatory data on harms for the included
interventions … page 12, the Data Synthesis section describes the range
and inconsistency of outcome measures. … For KQ1A, risk
of bias associated with blinding of patients
and personnel and incomplete outcome data … Similarly, although
costs are certainly a factor in access and use of care, there is
no data that helps
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - In the United States there has been
a near disappearance of the use of FGAs
Purpose of Review:
To … Data Synthesis
For each KQ, we synthesized data in the following order
based on type of drug comparison … The main contributor to ROB was incomplete outcome
data. … For the outcome of EPS symptoms, we
included data from findings on (in hierarchical order)
akathisia … Research Gaps
The following general recommendations for future
research are based on the preceding
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
February 04, 2014 - use of surgery. … versus retrospective)
– Use of an independent outcome assessor
The quality of the abstracted studies … to a given outcome, based on the
sufficiency of sample size and number of
events. … For assessing a clinical outcome, RCT evidence is
considered the best evidence, based purely on study … outcome lead to a rating of direct on the directness domain.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
February 01, 2019 - of the Interagency Pain Research Coordinating Committee
(IPRCC), and creation of a federal portfolio … of existing pain research to help inform additional
research needs on pain. … These initiatives, along with the recent
publication of the evidence-based guideline on opioid use for … , for function as
a mean difference of 10 to 20 points on the ODI or 2 to 5 points on the RDQ, and for … Institute of Medicine Committee on Advancing Pain Research C, Education.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
February 01, 2013 - Should effectiveness research on PT treatments use MCIDs? … Should effectiveness research on PT treatments use MCID? … priorities. … Should effectiveness research on PT treatments use MCIDs? … research demonstrate the
use of a wide variety of outcomes measures.
14,20
The CER emphasized that
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_disposition-comments.pdf
December 01, 2011 - If no other evidence on an outcome of interest was
available, however, we may comment on findings from … have had the only relevant information on a major
comparison or outcome, we will cite this information … the Agency for Healthcare Research and
Quality (AHRQ) included it on the list of medications of interest … The data was reported as a graph only. … Statistical heterogeneity also depends on the
outcome measure of choice.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
September 20, 2017 - (IPRCC) and creation of a federal portfolio of existing pain research to help
inform additional research … The recent
publication of evidence-based guidelines on opioid use for chronic pain by the Centers
for … Disease Control (CDC),11 which includes a recommendation on the preferred use of
non-opioid treatment … In determining the strength of a body of evidence for each prioritized primary or
safety outcome, the … • Precision: describes the level of certainty of the estimate of effect for a
particular outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nursing-home-safety_research-protocol.pdf
July 22, 2015 - Early and ongoing research has focused in large part on the use of secondary
data analyses, rather than … Moreover, serious deficiencies in the accuracy of NH self-
reported outcome and process data have been … What is the state of the current research based on the following criteria:
a. … Sources of outcome data (i.e., facility self-report versus resident/family self-report
versus objective … A controlled, randomized, comparative study of a radiant heat
bandage on the healing of stage 3-4 pressure
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - are available, only outcome data from the report
with the largest number of patients will be included … We will make an exception and
include data from a smaller study when it reports data on an outcome that … A descriptive, narrative review approach will be used to synthesize data from studies
reporting on the … A rating of insufficient will be given when the evidence does not
permit a conclusion for the outcome … Did the patients in different study groups have similar levels of performance on the
outcome of interest
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
March 19, 2018 - TEP reviewer #3 It would also be useful to give a summary of the
outcome variable and the SOE based … Conclusions are
always solidly based on the specific KQs and on
an objective assessment of the data … based upon the data reviewed and discussion of
the data. … The conclusions of this “technical”
analysis are soundly based on the data available. … As a pediatric asthma
clinician, I found the discussion on the 0-4 year
old use of intermittent ICS
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries_research-2012-2_1.pdf
January 01, 2012 - This report is based on research conducted by the Outcome DEcIDE Center under contract to the
Agency … Because the RoPR is a voluntary system, burden of use is a major consideration. … optimizing
the use of limited health care research resources. … (Prepared by Outcome DEcIDE Center
[Outcome Sciences, Inc. d/b/a Outcome] under
Contract No. … Terms and Conditions for Use of
ClinicalTrials.gov Data. ClinicalTrials.gov.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-march-2023-grand-rounds-slides.pdf
January 01, 2023 - (ACCME) through the joint providership of OHSU School of
Medicine and the Agency for Healthcare Research … 7
Poll
How would telehealth
research be of most
use to you? … ) might increase the impact of future research? … to be tailored to frequency of use
Rapid increase in the use of telehealth in response to the COVID … or confirm equivalence
Data limitations
• Use of retrospective data
• Data produced for care delivery
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
June 16, 2010 - outcome is cure due to the
absence of studies that adequately characterize the impact of EPOGEN® on … outcome is cure due to the absence of studies that
adequately characterize the impact of Aranesp® on … “intention-to-treat” and
“as treated” analyses, we will use the intention-to-treat based data for a … Because of the problematic use of quality summary scores,46,47 we will use a
quality assessment form … On some specific
reports such as reports requested by the Office of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
January 01, 2009 - The best way to evaluate the effects of testing on
patient outcome is a randomized controlled trial, … effect on patients from testing should have
a clinical measure as the primary outcome. … as the use of resources, length of stay, or satisfaction, or they
concentrate on the results of testing … will also collect data on secondary
outcome measures. … on clinical outcome will depend on the magnitude of the latter.
-
effectivehealthcare.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
January 01, 2009 - The best way to evaluate the effects of testing on
patient outcome is a randomized controlled trial, … effect on patients from testing should have
a clinical measure as the primary outcome. … as the use of resources, length of stay, or satisfaction, or they
concentrate on the results of testing … will also collect data on secondary
outcome measures. … on clinical outcome will depend on the magnitude of the latter.