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effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - Data Abstraction and Data Management
At the beginning of data abstraction, we will develop a standardized … process, intended interventions,
missing outcome data, outcome measurement, selective reporting, and … each outcome: data source, effect size, SOE rating; and rationale for
judgments made on each domain … Research and Quality or the U.S. … Data Abstraction and Data Management
D. Assessment of the Risk of Bias of Individual Studies
E.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - None of the nonrandomized comparative studies reported
data on hospital days or data on medication use … Comparative data with
respect to angiography alone were available on the use
of FFR, which measures … In addition, our review
synthesizes data and analyzes gaps in the literature on the
use of intravascular … Future research
is also needed to assess the usefulness of how these
procedural data are presented, … Impact of
intravascular ultrasound-guided stenting on long-term
clinical outcome: a meta-analysis of
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effectivehealthcare.ahrq.gov/sites/default/files/suppl-1-user-guide-to-ocer_130129.pdf
January 01, 2011 - On the “support” A research objective is described as being on the “support” of a
research database … whose data are
available for the research. … , and Identification
If a researcher is to make inferences on the
effects of treatment (T) on outcome … direct effect on outcome (Y). … Econometrics in
outcomes research: the use of instrumental
variables.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_disposition-comments.pdf
August 12, 2016 - Further, the widespread use of statins
which have a profound effect on vascular outcomes and the decline … But
diabetes is not a CVD
outcome, nor was it
considered to be a standard
CVD intermediate outcome … While a worthy
outcome for evaluation, it did
not fall within the purview of
this review. … BP was not a newly added
outcome. … According to page 102 of the
report, for systolic and diastolic blood pressure, data on the effect of
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults_research-protocol.pdf
December 20, 2011 - The appropriateness of a
particular setting for an LTC recipient is based on a complex interplay between … We will abstract data on
characteristics of population served from cross-sectional studies and studies … differences; intervention specification; the
completeness of followup; and use of equivalent outcome … Specific data fields are noted in the data management section. … To compare outcomes of care across settings, we will first categorize studies by
the outcome domain
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - None of the trials provided data on hard
end points like mortality and stroke. … Data Abstraction and Data Management
The research team will create data abstraction forms for the KQs … The grading will be outcome-specific such that a given study that analyzes its primary
outcome well … We will
use a checklist to guide the assessment of applicability. … in use, the
possibility of surgical learning curves, and clinical relevance and timing of the outcome
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-appendix-c.xlsx
January 01, 2024 - Effect of a Wireless Vital Sign Monitoring System on the Rapid Response System in the General Ward. … Pooling of data indicated that use of WMS did reduce ICU transfer (RR 0.87; 95% CI 0.66–1.15), but not … All clinical complications--A total of five studies reported data on complication outcomes classed by … This was added along with the use of the Between the Flgas EWS. … care Reduce telemetry use on a hospitalist service using educational modules, routine review, and financial
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - diarrhea.9
Exercise Training
Over the past 30 years, research efforts within PAD
have focused on … in the development of the research
protocol. … a decision to include or exclude the article
for data abstraction. … incomplete data were addressed appropriately;
the validity of outcome measures; and conflict of interest … Meta-analyses were based on the nature of the outcome
variable, but random-effects models were used
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hnhc-disposition-comments.pdf
October 29, 2021 - in the
development of its research projects. … predictor of future use
and an outcome. … patients based on their healthcare use, we had
limited information on other services that could be … We highlighted the heterogeneity
of patients as a limitation in drawing conclusions on the effectiveness … any studies concerning the impact of COVID-19 on
these patients, as a reviewer had hoped.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
January 01, 2010 - report defined comparative effectiveness research as a rigorous evaluation of the impact of different … Research on the comparative effectiveness of medical treatment. … A key reason to consider the use of observational studies when selecting evidence for comparative effectiveness … The types of OSs included in a comparative effectiveness research will vary. … rendered irrelevant based on the availability of data from stronger study types.
-
effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
January 01, 2010 - report defined comparative effectiveness research as a rigorous evaluation of the impact of different … Research on the comparative effectiveness of medical treatment. … A key reason to consider the use of observational studies when selecting evidence for comparative effectiveness … The types of OSs included in a comparative effectiveness research will vary. … rendered irrelevant based on the availability of data from stronger study types.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
June 01, 2017 - Despite efforts to spur pediatric research, there is a paucity of pediatric-specific
research data available … Terminology
We use the term study to refer to the conducted research. … Blinding of
personnel/care
providers
Blinding
of
outcome
assessor
Incomplete
outcome
data … Outcome reporting in industry-sponsored
trials of gabapentin for off-label use. … Clinical
trial registries are of minimal use for
identifying selective outcome and analysis
reporting
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
November 08, 2012 - experiencing at least one traumatic event in their lifetimes.3
Most of the research has focused on … If we cannot find data on a particular health outcome of
interest, we will include surrogate outcomes … To assess the risk of
bias (internal validity) of studies, we will use predefined criteria based on … We
will consider the risk of bias for each relevant outcome of a study. … similar studies, or insufficiency or variation in
outcome reporting), we will synthesize the data qualitatively
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
August 10, 2022 - results of a study, or if we are aware of unpublished data, we will
query the authors to obtain this … of additional therapies), and outcome measurement as data permit. … Based on this prioritized list, the strength of
evidence for comparison-outcome pairs within each KQ … , medium, or high level of study limitations)
o This is the degree to which studies for a given outcome … level of certainty of the effect estimate for a particular
outcome with a precise estimate being one
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
January 17, 2017 - We have added information about the utility of
commonly used outcome measures to the
Research Gaps … We have added a definition of OSA, but we do
not use the term SDB in the report. … We agree that additional data are
needed to inform analyses and have added a
statement to the research … symptoms, use of
perioperative steroids), but the review did not
address all areas touched on in the … We have
expanded our discussion of outcome measures
in the Research Gaps section of the Discussion.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
November 01, 2014 - Trained reviewers recorded relevant
data from the studies; a second member of the team
reviewed all … ) of
studies, we applied predefined criteria based on the Agency
for Healthcare Research and Quality … We determined that very little research has focused on
the use of PK/PD measures in dosing or monitoring … Evaluating either the
development or the prevention of resistance is a difficult
research endeavor. … While PK/PD dosing
strategies are supported by concept, the lack of prospective
patient outcome data
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
January 01, 2016 - librarian employed search strategies (Appendix A of the
full report) to retrieve research on diagnostic … , and
baseline and outcome data on constructs of interest. … This model
allowed several different types of outcome data and a
suite of pharmacologic interventions … Studies are also limited by the use of multiple and variable
outcome measures to assess resolution of … Limited research is available to guide decision-making
about the use of laser modalities as the initial
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_disposition-comments.pdf
June 05, 2013 - We have changed "a" to "on"
Peer Reviewer 5 Methods Weight loss is as much an indirect outcome as HbA1c … Weight loss is an intermediate outcome in terms of being
on the pathway to improvement in comorbid conditions … As there are no long
term data on surgery in this BMI range but clear data on bigger
folk from the … the outcome data
need to be developed and standardized so that long-term data
initiated now will be … need for long term
robust outcome data for surgery.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
October 14, 2011 - However, use of
this test without a systematic review of current evidence has the potential to create … Data abstraction tables will be pilot tested for completeness on a group of select
12
Source: … Did the analysis of outcome data incorporate a method for handling confounders such as
statistical … Did the authors provide a rationale and ‘‘a priori’’ design for the review, and were the
research questions … the use of a smaller
number of cores (6, 8, or 10) per biopsy.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bimp-protocol.pdf
September 27, 2022 - The final Research Protocol will be used to guide a systematic review of the
evidence by researchers … A second
analyst will perform a quality check of 10% of extracted data for accuracy. … • Missing outcome data
• Measurement of the outcome
• Selection of the reported result
Two reviewers … powering trials, for headache frequency, we will use a difference of 1
migraine day/month as the MID … We will assign a rating of Insufficient when the evidence does not permit a conclusion for the
outcome