-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
January 01, 2010 - oxygen saturation did not have a significant
effect on the overall use of cesarean, however three of … on the overall use of cesarean;
however three of the four studies looking at the use of fetal
pulse … Well designed research of sufficient power to detect the
ultimate outcome - use of cesarean - is very … there is a unique burden on the discussion
section to provide a synthesis that can transform a “data … The
focus on over sample size vs a criterion of power analysis
base on primary outcome should be rethought
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
June 12, 2014 - 5 (Santaguida, 2012).11 We will use the QUADAS-2
instrument for studies on test accuracy; domains and … for a given
outcome or comparison have a high
likelihood of adequate protection
against bias (i.e … directness of the
overarching question, if there are no studies
linking the test to a clinical outcome … is the case); namely, use of
intermediate/surrogate outcomes rather than
health outcomes, and use … A
commentary on the current practices of members of the European Society for Paediatric
Gastroenterology
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_disposition-comments.pdf
August 21, 2013 - Two researchers worked on
each of the Key Questions, verifying the data
extraction and interpretation … Balbuena
used data from all patients on clozapine for a
minimum of 6 weeks and Martin et al. enrolled … For
use of between-group comparisons of outcome
data as problematic. … Both modified therapeutic community trials
reported substance use as an outcome. … Where is the outcome data for these programs
that our courts continue to utilize?
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-evidence-summary-updated-1.pdf
October 01, 2021 - Based on the type of procedure and composition of the newly
reconstructed breast, reconstruction is … Use versus nonuse of human ADMs during IBR: ADM use probably increases the
risk of implant failure/loss … Upon re-review of the studies, we found that only a single study reported relevant data
for this comparison … The SoE was downgraded from low to insufficient based on a single study
with high risk of bias and imprecise … Based on this, a conclusion cannot be made for
this comparison.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
March 01, 2014 - Data Extraction
The research team created data abstraction forms and
evidence table templates for each … Based on clinical
and methodological expertise, a pair of investigators
was assigned to abstract data … data
on treatment. … In general, we considered use of a symptomatic
treatment in a population with a known underlying
etiology … Data on
nonpharmacological therapies for chronic cough are
extremely limited, as are data on the management
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
March 05, 2015 - use: a pooled analysis. … KQ2 was a review of reviews, and relied on the
USPSTF report, which is effectively silent on the
matter … While report considered trial data on a number of important
menopausal sx in addition to vasomotor sx … Data from trials meeting the inclusion
criteria have been added to this report.
2. Use of SMD. … A review of
evidence for all safety data for the nonhormonal
agents was beyond the scope of the review
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
July 09, 2014 - A lack of conceptual clarity around cultural competence persists in the field and the
research community … of participants and personnel, blinding of outcome assessment,
incomplete outcome data (i.e., was incomplete … outcome data adequately addressed),
selective reporting, and other sources of bias (i.e., problems … Based on these factors, the overall strength of evidence for each outcome
will be rated as:12
• High … Losing culture on the way to competence; the use and misuse
of culture in medical education.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-appendix-d.xlsx
January 01, 2024 - Importantly, Claude 2's ease of use was high
37803451 Panayi, A., Ward, K., Benhadji-Schaff, A., Ibanez-Lopez … Creating efficiencies in the extraction of data from randomized trials: a prospective evaluation of a … Creating efficiencies in the extraction of data from randomized trials: a prospective evaluation of a … Creating efficiencies in the extraction of data from randomized trials: a prospective evaluation of a … Creating efficiencies in the extraction of data from randomized trials: a prospective evaluation of a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
February 05, 2025 - Data Abstraction and Data Management
At the beginning of data abstraction, we will develop a standardized … process, intended interventions, missing
outcome data, outcome measurement, selective reporting, and … If a meta-analysis is
deemed appropriate, we plan to use the DerSimonian and Laird random-effects method … : data source, effect size, SOE rating, and rationale for judgments made on each domain
of evidence … and Data Management
Assessment of the Risk of Bias of Individual Studies
Data Synthesis
Grading the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - is controversial mainly
because of limited high quality and longitudinal data on which to base conclusive … If a study mentions an adverse event in the discussion but does not
report data on that adverse event … data, selective outcome reporting, and
“other” sources of bias) and a categorization of the overall … Each assessment form will be pilot tested on a sample of studies. … On some specific reports such as reports requested by the Office
of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - The systematic review literature itself rests on a large body of
experimental literature. … of participants and personnel, blinding of outcome assessment,
incomplete outcome data (i.e., was incomplete … When standard
MIDs for a particular outcome is not available, we will use a statistical difference to … Based on these factors, the overall strength of evidence for each outcome will be
rated as:19
• High … "A systematic review of the global distribution and
availability of prevalence data for bipolar disorder
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infertility_research-protocol.pdf
October 12, 2015 - data on the long-term safety of multiple courses of ovulation induction for the
purposes of oocyte donation … data on
U.S. population-based outcomes for ART, it is limited by (a) use of the ART cycle (rather than … Data Abstraction and Data Management
The research team will create data abstraction forms for the KQs … Myers to accommodate specific questions.61 We will use
suggested guidance on the use of simulation models … in use, the possibility of surgical learning
curves, and clinical relevance and timing of the outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
April 01, 2015 - estimates has to depend on the reported data. … has been a call to use alternative random-effects estimates to
replace the universal use of Dersimonian-Laird … For each review, we abstracted data
on whether continuous outcome and meta-analysis were used, the effect … The use of MD versus SMD typically depends on the scales of the included outcomes. … but did not use data from the CERs in our
evaluation, as the data from the CERs were not adequate for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ankyloglossia_research-protocol.pdf
June 30, 2014 - line to form a proper seal and therefore use their jaws to keep the breast in
the mouth. … Uncertainty is further promulgated by absence of data on
the natural history of untreated ankyloglossia … of the frenulum with age and use.1
However, there are no prospective longitudinal data on the fate … Within each KQ, we will organize results by study design and
outcome, with a focus on those designs … We will use explicit criteria for rating the overall strength of the evidence for each key
intervention-outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - A review of the current available data can help shed light on areas that require further
clinical investigation … Data Abstraction and Data Management
The research team will create data abstraction forms for the … We will use a checklist to guide the
assessment of applicability. … in use, and clinical relevance and timing of the
outcome measures. … event and effect on clinical outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mgmt-hnhc-patients-protocol.pdf
November 07, 2019 - A large percentage of high-cost patients use this
level of care for a relatively short period of time … In the end, we will present a
summary of the data and syntheses of the evidence and our conclusions … Data Synthesis
Realist Review: Three Main Targets of Analysis
In a realist review, the goal of the … If we find three or more studies for a comparison of an outcome of interest, we will consider
pooling … Methods for the synthesis of qualitative research: a critical
review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
November 28, 2023 - Dietary Guidelines for Americans do not list protein as
a nutrient of concern based on the fact that … enroll some
participants diagnosed with
a disease or with the health
outcome of interest
● Participants … data;
4) Bias in measurement of outcome; 5) Bias in selection of reported result. … The
Human Milk
Composition
Initiative: Filling
Crucial Gaps in
Data on and
Related to Human
Milk … Scanning for New
Evidence on the
Nutrient Content
of Human Milk: A
Process Model for
Determining
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
April 01, 2022 - the strength
and limits of evidence from research studies about the effectiveness and safety of a clinical … : a retrospective case-
control study based on data from the
Osteoarthritis Initiative (OAI). … Predictors of Prolonged Opioid Use After
Lumbar Fusion and the Effects of Opioid
Use on Patient-Reported … Comparison of the use of opioids only and
pregabalin add-on for the treatment of
neuropathic pain in … Two
data-driven approaches to identifying the
spectrum of problematic opioid use: A pilot
study within
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alternative-payment-models-protocol.pdf
December 16, 2024 - Research on total healthcare costs as well as implementation
costs from a payer or societal perspective … This will be documented together with information on the control (e.g., data before the
implementation … limitations: The extent to which studies that report on a particular APM and outcome are
likely to … for a particular outcome; graded as consistent, inconsistent, or unknown (in the case of a single
study … • Imprecision: Determines the level of certainty of the estimate of effect for a particular
outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
September 20, 2013 - use of a reference standard and the reporting of information on
test performance outcomes. … We will also perform a search for systematic reviews on the topic and use their reference lists of
included … and outcome data. … Of note, the material used to solicit TEP input will not include any data
on outcome results extracted … “indirect”) on the basis of the use of surrogate outcomes or the need for indirect
comparisons.