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Showing results for "a research on the use of outcome data".

301. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
     February 19, 2010 - Intervention: The intervention is the use of a neurothromectomy device with or without intravenous or … The intervention is the use of a neurothromectomy device with or without IV or IA thrombolytic therapy … We will finalize a database of the available neurothrombectomy devices with information and data provided … Data Abstraction and Data Management Through the use of a standardized data abstraction tool, two reviewers … On some specific reports such as reports requested by the Office of Medical Applications of Research

302. Suicidal-Thoughts-Young-People-Amendement-May-2025 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
     January 01, 2025 - Data Abstraction and Data Management At the beginning of data abstraction, we will develop a standardized … process, intended interventions, missing outcome data, outcome measurement, selective reporting, and … If a meta-analysis is deemed appropriate, we plan to use the DerSimonian and Laird random-effects method … : data source, effect size, SOE rating, and rationale for judgments made on each domain of evidence … and Data Management Assessment of the Risk of Bias of Individual Studies Data Synthesis Grading the

303. Disposition of Comments Report for Treatment of Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
     June 28, 2013 - was to use the outcome as stated in the published paper. … With regard to use of an alternative placement when the initial placement fails, we have added data … While this is a laudable and interesting research question, I could not find the supporting data in … between the outcome and a health outcome. … With regards to use of an alternative placement when the initial placement fails, we have added data

304. labor-dystocia-protocol-amended-160728 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
     July 28, 2016 - dilation until delivery of the infant), developed based on data from the Safe Labor Consortium.3 … Data Abstraction and Data Management The research team will create data abstraction forms for the … The grading will be outcome-specific such that a given study that analyzes its primary outcome well … We will use a checklist to guide the assessment of applicability. … Evaluating the Potential Use of Modeling and Value-of-Information Analysis for Future Research Prioritization

305. Making Healthcare Safer IV Rapid Review: Prevention in Adults of Infection With Transmission of Multidrug-Resistant Organisms (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-rapid-research.pdf
     April 01, 2024 - MHS I (2001) chapter 13 primarily focused on the use of barrier precautions in the prevention of HAIs … The risk of bias assessments focused on the main outcome of interest in each study.13 For recent … reporting of certain infection data to NHSN depending on the type of healthcare facility. … The investigators also reported a 29 percent lower risk of the secondary outcome of hospitalization … From Laboratory Research to a Clinical Trial: Copper Alloy Surfaces Kill Bacteria and Reduce Hospital-Acquired

306. EHC Protocol: Recurrent Nephrolithiasis in Adults and Children: Comparative Effectiveness of Preventive Medical Strategies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
     September 24, 2024 - preferences.1 The 2012 Agency for Healthcare Research and Quality (AHRQ) review on this topic found … One reviewer will abstract the data into the forms, and a second reviewer will check the data for accuracy … In some cases, we may report an outcome-specific ROB rating within a study if we assess the outcome … the estimate of effect lies close to the true effect for this outcome. … Use of thiazide diuretics for the prevention of recurrent kidney calculi: a systematic review and meta-analysis

307. Disposition of Comments Report for Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
     January 01, 2014 - that the use of low dose aspirin has supporting data. … The original question was on the effectiveness and safety of long-term use of PPIs, so only postdischarge … We also corrected the use of data in the sentence (“these recent data”). … the data and the areas of need for future research. … be data for each outcome of interest.

308. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-screening_research-protocol.pdf
     October 20, 2011 - of HCV infection as a clinical outcome (incorporates transmission) Question 1 This KQ has … To identify articles relevant to each KQ, a research librarian will search the Cochrane Database of … based on predefined criteria, assessing whether they had a clear statement of the research questions … We therefore will not use a formal scoring system to rate the risk of bias in observational studies … Appropriate measures will be chosen based on the type of data for meta-analysis.

309. Transparency of Reporting Requirements: Omega-3 Fatty Acids and Cardiovascular Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
     September 02, 2016 - development of search methods, data collection, and evaluation techniques to optimize the use of trial … Methods Overview We will use a completed systematic review conducted by our EPC on the relationship … Terminology We use the term study to refer to the conducted research. … to amount, nature or handling of incomplete outcome data There is a LOW RISK OF BIAS if there were … There is a LOW RISK OF BIAS if there were no missing outcome data; reasons for missing outcome data

310. MEDICAL MANAGEMENT OF CONGESTIVE HEART FAILURE AND THE EFFECTIVENESS OF ISOSORBIDE DINITRATE AND HYDRALAZINE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
     March 01, 2010 - The absence of data on the clinical severity of HF and left ventricular function, potent predictors … of therapy prior to the occurrence of a primary outcome or censorship. … From prescription and outcome data on more than half a million patients with a diagnosis of HF, we … A review of uses of health care utilization databases for epidemiologic research on therapeutics. … Elixhauser A, Steiner C, Harris DR, et al. Comorbidity measures for use with administrative data.

311. Fractional Exhaled Nitric Oxide Clinical Utility in Asthma Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-nitric-oxide_research-protocol.pdf
     September 06, 2016 - The review also will highlight areas of controversy and identify needs for future research on this priority … Data Abstraction and Data Management At the beginning of data abstraction, we will develop a standardized … assessor blinding; attrition bias; incomplete outcome data; selective outcome reporting; and other … Based on this assessment and the initial study design, we will assign a strength of evidence rating … : data source, effect size, strength of evidence rating; and rationale for judgments made on each domain

312. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
     June 01, 2022 - the strength and limits of evidence from research studies about the effectiveness and safety of a clinical … : a retrospective case- control study based on data from the Osteoarthritis Initiative (OAI). … Predictors of Prolonged Opioid Use After Lumbar Fusion and the Effects of Opioid Use on Patient-Reported … Comparison of the use of opioids only and pregabalin add-on for the treatment of neuropathic pain in … Two data-driven approaches to identifying the spectrum of problematic opioid use: A pilot study within

313. The Effect of Protein Intake on Health (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
     November 29, 2023 - We will review and agree on the search strategies through a consensus by the team members. … of the outcome; 5) Bias in selection of reported result. … A systematic review and meta-analysis of observational studies on the association between animal protein … Care Interventions for the Effective Health Care Program of the Agency for Healthcare Research and … This systematic review focuses on dietary protein; and a report on only the % calories from protein

314. Tinnitus Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
     August 01, 2013 - were included under the category of “discomfort.” bThe outcome “severity” was added during data extraction … data and results All KQs: Possibility of extracting relevant outcomes from data in the papers Controlled … epidemiological research on adults over the age of 45 years.4 The finding of generational differences … data on the medium- to long-term effects of the active treatments. … • Collect information on the use of concomitant interventions.

315. CER 225: Evidence Summary Interventions for Substance Use Disorders in Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-evidence-summary%20225%20Substance%20Use%20Adolescents.pdf
     May 01, 2020 -  More research is needed to understand the role of medications in treatment of alcohol and cannabis … adults with problematic substance use or a diagnosis of a substance use disorder (SUD), excluding tobacco … incomplete outcome data, poor compliance, and a lack of blinding of participants, study personnel, … and outcome assessors. … Among intensive interventions, family therapy (with a focus on intervening in the entire family system

316. Diagnosis and Management of Obsessive Compulsive Disorders in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
     August 15, 2023 - We typically use a threshold for the prediction score of the unscreened citations of 0.40 (this threshold … Questions related to outcome assessor blinding, missing data, outcome measurement reporting adequacy … Tool26 that pertain to participant loss to follow up, incomplete outcome data, and selective outcome … We will prefer continuous effect metrics on the original scale, rather than use standardized effect … the process of care on the patient’s experience) PROM Patient-reported outcome measure (that reflects

317. Pharmacologic Management of Acute Pain by EMS in the Prehospital Setting Protocol Amendment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
     January 28, 2019 - the appropriate use of prehospital opioids is the fear of their abuse and the resulting epidemic in … data on the outcomes of interest. … given the identified limitations.19 Data Synthesis - For each KQ, we will create a set of detailed … The effectiveness and adverse events of morphine versus fentanyl on a physician-staffed helicopter. … for rare event outcome: a simulation study.

318. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
     May 01, 2017 - or contexts • Sufficiently detailed methods and results to enable data extraction • Reporting of outcome … to a given agent over time, studies typically did not provide data to determine the initiation of … Data were inadequate in a small study of guanfacine to draw conclusions about effects on any outcomes … , with little data on the treatment of younger children. … In addition, much of the medical intervention literature relies on baseline and outcome measures that

319. Disposition of Comments for Venous Thromboembolism Prophylaxis in Orthopedic Surgery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
     March 01, 2012 - We cannot reliably use data from 20-30 years ago (published in the 80s and 90s) since the patterns of … Therefore, guidance on proposed research would be to fund clinical trials that produce data that give … The impact of the method of prophylaxis on VTE and bleeding outcome was evaluated in the other KQs in … of use of the drug. … For outcome 4, there is no reason to change strategy unless there is a significant cost or ease-of-use

320. Disposition of Comments for CER 182 Glasgow Coma Scale (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow-disposition-170415.pdf
     January 12, 2017 - Further the bias of missing data may also be a factor. … The importance of “small” differences in discrimination depends in part on the seriousness of the outcome … We revised the Future Research Needs section to mention the impact of educational efforts on interrater … on the AUROC, a measure of discrimination. … Thus, a tailored approach to selecting the use of tGCS vs mGCS/SMS based on "local provider capabilities