-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - We acknowledge that
both types of reporting bias are difficult to reliably detect
on the basis of data … One hundred and thirty-one study groups reported the
use of a single form of imaging guidance (83 stereotactic … of data. … Because delayed diagnosis on the basis of biopsy results
is the most important (adverse) outcome related … The next focus of research should be biopsy under
MRI guidance, which is a new technique that is likely
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
April 25, 2013 - While we agree that funding issues may preclude
addressing some of the stated research priorities, we … We have added points to the research gaps section:
- Further development of data on the use of echo … outcome data, or data on mortality. … outcome data, or data on mortality. … The research gaps could use some refining.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_executive.pdf
January 01, 2014 - Despite these recent data, a number
of questions remain about the use of antiplatelet and
anticoagulant … • With planned GPI use, bivalirudin reduced the rate of
the composite outcome of all-cause mortality … There was a paucity of data on the optimal timing of
oral antiplatelet agents as initial treatment for … of use of these
agents based on the type of stent used during PCI. … The final research gap for KQ 3 is the limited and
inconsistent data on long-term anticoagulant therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicide-prevention_disposition-comments.pdf
October 04, 2016 - on a national level, even for
routine sharing of clinical data; the lack of
adequate access to data … But I think its essential to clarify
that selection of the right source depends on the outcome
of interest … , (3)
familiarity of the research team experts
with the data systems of those states. … The legal feasibility of
linkage depends on the applicability to the
specific purpose of the data linkage … They also did a good job interpreting the data in
the context of current challenges to research and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-protocol.pdf
July 01, 2023 - Making Health Care Safer (2001) chapter 13 primarily focused on the use of barrier precautions in the … Depending on the
expected volume of literature, the EPC team may opt to have a randomly selected 10% … sample of
articles checked by a second reviewer or use the artificial intelligence (AI) feature of … , as described below in
the section on Data Extraction. … will focus on the
main outcome of interest in each study.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/postpartum-care-one-year-protocol-amendment.pdf
April 25, 2022 - We typically use a threshold for the prediction score of the unscreened citations of 0.40 (this
threshold … /care providers, objective outcome assessors, and subjective outcome assessors; incomplete
outcome data … We will also use
items from the NHLBI Tool focusing on the adequacy of descriptions of study eligibility … , we will also use the items from the Cochrane Risk of Bias Tool16 that focus on issues
related to blinding … ; incomplete outcome data; selective outcome reporting; and other issues that
could be related to bias
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
September 01, 2010 - There are many controversies in
the field: (1) Is the use of combination therapy with a thiopurine agent … Initial data suggest it
cannot be.19 The major challenge and focus of current research is improving … strategies; and further evidence on optimizing the
use of biologic agents given that many patients’ … We will use a systematic approach for extracting data to minimize the risk of bias in this
process. … On some specific reports such as reports
requested by the Office of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
September 03, 2019 - The use of emergency
department data as surrogates for prehospital is
logical, in the absence of field … ,
and the use of a medical librarian is appropriate
No comment. … If the dose was not described, the data are really
not suitable to use for the kinds of comparisons … it is preferable to conclude
that the data cannot support a particular
recommendation or outcome. … there is a ton of
data, it is very dirty and inconclusive and we need
more research.
-
effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
February 01, 2008 - One disagreement
between the two sets of guidelines is in the use of DVT as a surrogate marker for PE … impacting the surrogate marker also predicts the effect on the clinical outcome of
interest.5,6 In … Data Abstraction and Data Management
Two reviewers will use a standardized data abstraction tool to … filters), mobilization status of the patients, use of
concurrent standard medical therapies, data needed … On some specific reports such as
reports requested by the Office of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
February 01, 2008 - One disagreement
between the two sets of guidelines is in the use of DVT as a surrogate marker for PE … impacting the surrogate marker also predicts the effect on the clinical outcome of
interest.5,6 In … Data Abstraction and Data Management
Two reviewers will use a standardized data abstraction tool to … filters), mobilization status of the patients, use of
concurrent standard medical therapies, data needed … On some specific reports such as
reports requested by the Office of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
December 18, 2019 - Based on data
from trials of labor induction, approximately 83 to 85 percent of women with an indication … Key Questions
An initial set of Key Questions (KQs) were posted on the Agency for Healthcare Research … issues in a review for which a valid, but not necessarily systematic, summary
of current research is … Based
on this prioritized list, the strength of evidence for comparison-outcome pairs within each Key … to a specific
outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading-quiz.ppt
May 29, 2025 - to a specific outcome), consistency (i.e., degree of similarity in the effect sizes of different studies … a single, direct link between the interventions of interest and the ultimate health outcome under consideration … of certainty for estimate of effect with respect to a specific outcome). … that one cannot use any of the other levels. … Lohr, Ph.D., a Distinguished Fellow at RTI International, and is based on an update of chapter 11 in
-
effectivehealthcare.ahrq.gov/sites/default/files/grading-quiz.ppt
May 29, 2025 - to a specific outcome), consistency (i.e., degree of similarity in the effect sizes of different studies … a single, direct link between the interventions of interest and the ultimate health outcome under consideration … of certainty for estimate of effect with respect to a specific outcome). … that one cannot use any of the other levels. … Lohr, Ph.D., a Distinguished Fellow at RTI International, and is based on an update of chapter 11 in
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
January 12, 2022 - , based on
Medicare data of approximately 1.7 million individuals, is 27.3%, with the highest
prevalence … (e.g., age,
gender, severity of disease), and outcome measurements as data permit. … Based on this prioritized list, the strength of evidence for
comparison-outcome pairs within each KQ … is the degree to which studies for a given outcome are likely to have
reduced bias based on study design … level of certainty of the effect estimate for a particular
outcome with a precise estimate being one
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
November 01, 2010 - In fact, this is noted as a topic on
which there is a paucity of data. … There is a paucity of published
data on the impact of child characteristics on
outcome that have been … differences on the outcome
varies as a function of the "characteristic" or
"moderator". … on the short-term RCT data). … Discussion Even more emphasis on the need for a priori
targeting of outcomes and then standard outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-health-systems-guidelines-development.pdf
February 01, 2019 - This follow-on
research would provide realistic data on the resources needed to generate systematic … priorities. … Each
row corresponded to a single, separate outcome; columns corresponded to data on that single
outcome … Effects of an evidence service on health-
system policy makers' use of research
evidence: a protocol … Data on demand: A model to
support the routine use of quantitative data
for decision-making in Access
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - We welcome comments on this Methods Research Project. … None of the studies changed a primary outcome to a
secondary outcome. … data on quality of life.
31
Table 17. … In particular, the limited reporting of results in
ClinicalTrials.gov hindered our ability to use the … we could use in our systematic review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_executive.pdf
May 01, 2014 - One
investigator extracted the relevant data from each included
article; a second member of the team … data,
reliability and validity of outcome measures, and treatment
fidelity. … We
also considered resource use as a dimension of intensity,
such as the total number of intervention … Data based on Medicare
claims suggest that 35 percent of 30-day readmissions are
for HF; the remainder … Future research of transitional care interventions could rely
on guidance from the AHA statement offering
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
February 04, 2025 - A second
reviewer will perform a quality check of the extracted data for completeness and accuracy. … If the
included studies for these questions include a variety of designs, we will use the Mixed Methods … Our decision to conduct
quantitative syntheses will depend on the number of studies, population, research … We will assign a rating of Insufficient
when the evidence does not permit a conclusion for the outcome … Precision is the degree of certainty surrounding an effect estimate concerning a given
outcome, based
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
May 01, 2019 - There are almost no data on the long-term safety
of multiple courses of ovulation induction for the … a large-scale,
population-based registry can achieve in terms of
providing data on treatment outcomes … However,
the major limitation of the database in the past
has been that data are only published on … Investigating
the effect of ethnicity on IVF outcome. … A Report on
the Priority-Setting Process, Preliminary Data Analysis,
and Research Plan.