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Showing results for "a research on the use of outcome data".

241. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
     May 14, 2010 - , and additional data on the efficacy of existing agents (zoledronic acid; calcium and vitamin D) have … of the use of pamidronate with deterioration of renal function.7,8 Based on these findings, AHRQ commissioned … criteria and will go on to data abstraction. … The data relevant to each outcome will be presented in individual tables. … On some specific reports such as reports requested by the Office of Medical Applications of Research

242. Cancer-Ovarian-Contraceptives Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
     June 01, 2013 - Data Synthesis After data extraction, we determined the feasibility of completing a quantitative synthesis … in use, and clinical relevance and timing of the outcome measures. … There are few available data on patient preferences relevant to the use of OCs as primary prevention … Better data on the relative quality-of-life effects of regular OC use, and the outcomes we reviewed … The effects of OC use on colorectal and breast cancer incidence were a major contributor to the overall

243. Disposition of Comments for CER 159 Insomnia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
     December 30, 2015 - We did not assess strength of evidence on this data. … a quantitative tallying of criteria, or a judgment on the part of the reviewers. … Revised text: ‘Based on these factors, the overall strength of evidence for each outcome was judged … a quantitative tallying of criteria, or a judgment on the part of the reviewers. … It relies on past systematic reviews and a new data extraction from the published literature.

244. Disposition of Comments Report for Interventions To Modify Health Care Provider Adherence to Asthma Guidelines (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_disposition-comments.pdf
     May 19, 2013 - of presentation of data and outcome measures and (c) testing interventions that target high risk groups … Magnitude is listed on the data tables but is not always discussed. … There is a significant amount of data given the number of interventions and outcomes being assessed … useful (e.g., based on a given outcome of interest, stakeholders can see the range of interventions … available and their impact on that outcome).

245. Ch 5-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
     January 01, 2012 - For example, consider an epidemiologic study of the effect of treatment A (exposed) on outcome Y. … treatment and, importantly, have no effect on the outcome of interest (supported by available evidence … For example, in a study assessing the risk of cancer in statin use,4 users of glaucoma drugs (like … may provide detailed data on the use of drugs, biologics, and devices and on the severity of underlying … When there is a dose effect on the outcome of interest, the dose of the exposure and comparison drug

246. Comparative Effectiveness Research Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disabilities-quality-improvement-outcomes_disposition-comments.pdf
     October 15, 2012 - effort to show relative values only, the use of pie charts implies actual data. … direct effect on the outcome, in addition to the effect of disease.” … Furthermore, the common data elements approach to increasing the consistency of outcome measures by … use of generic outcome measures that could be compared across diagnoses. … The use of data collection tools being used in PROMIS, was mentioned in the discussion of universal

247. Treatment of Osteoarthritis of the Knee: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-update_research-protocol.pdf
     June 15, 2016 - a consensus set of guidelines to assess the outcomes of research trials on products intended to treat … If primary outcome data appear to be lacking for a particular study or if peer reviewers note the existence … To assess the quality of prior systematic reviews that we include as sources of data, we will use the … impact on the effect size of omitting studies that use less common outcome measures. … the other included interventions (including a 2012 EPC review on the use of physical modalities to

248. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
     April 01, 2007 - common data definitions, and the use of patient identifiers. … purposes and the intended use of the data. … Determining whether the registry should use a case report form to collect AEs should be based on the … and outcomes on the association between the a priori exposure of interest and the outcome(s) … The practice of making inferences about causation largely on the outcome of tests of statistical significance

249. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
     June 12, 2012 - Guidelines have been published by the American Academy of Neurology on the use of pharmacologic agents … , population, number of subjects, research methods, and outcomes.35 We will also collect data on … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … data Described the completeness of outcome data for each main outcome, including attrition and exclusions … In an aggregated form such as a table, data from the original studies should be provided on the participants

250. Systematic Review Update: Noninvasive Nonpharmacologic Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
     December 11, 2018 - research needs on pain. … The recent publication of evidence-based guidelines on opioid use for chronic pain by the Centers for … Disease Control (CDC),12 which includes a recommendation on the preferred use of non-opioid treatment … from the published results of a study, or if we are aware of unpublished data, we will query the authors … • Precision: describes the level of certainty of the estimate of effect for a particular outcome

251. Treatments for Acute Pain: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-protocol-acute-pain-treatments.pdf
     August 08, 2019 - Recent data suggest an association between use of opioids for acute pain and persistent long-term use … from the published results of a study, or if we are aware of unpublished data, we will contact authors … , for function as a mean difference of 10 to 20 points on the ODI or 2 to 5 points on the RDQ, and for … estimate of effect for this outcome. … Effect of a single dose of oral opioid and nonopioid analgesics on acute extremity pain in the emergency

252. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
     November 24, 2014 - A review looking at use of PK/PD on clinical outcomes in a broader range of infections (e.g., treatment … Unfortunately though the included studies reported on a wide variety of pathogens, their outcomes data … There was a lack of data to support the use of continuous infusion of betalactam antibiotics compared … of studies would ever be competitive for federal funding given other research priorities). … Helps readers clearly understand the lack of data to support the use of PK/PD measures in guiding antibiotic

253. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-cough_research-protocol.pdf
     October 22, 2012 - Data Abstraction and Data Management The research team will create data abstraction forms for the KQs … The grading will be outcome specific such that a given study that analyzes its primary outcome well … We will use a checklist to guide the assessment of applicability. … We will use these data to evaluate the applicability to clinical practice, paying special attention … in use, and clinical relevance and timing of the outcome measures.

254. Future Research Needs for First- and Second-Generation Antipsychotics for Children and Young Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
     February 01, 2012 - Question Development and Research Design Considerations .................................... 9 Results … of reaching relative consensus on research priorities in this broad and complex topic area. … A total of 22 studies provided data on a variety of short- and long-term outcomes for patients with … Research Question Development and Research Design Considerations Using guidance from a draft AHRQ … of reaching relative consensus on research priorities in this broad and complex topic area.

255. FRN 29: Future Research Needs on Procalcitonin-Guided Antibiotic Therapy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
     August 01, 2014 - If pooling data across institutions is required, consensus on PCT cut-off points, standard care, outcome … If pooling data across institutions is required, consensus on standard care, outcome measures, minimum … Level 5 • Patient outcome: The impact of the test information on the risks and benefits to the patient … If pooling data across institutions is required, consensus on PCT cut-off points, standard care, outcome … If pooling data across institutions is required, consensus on standards of care, outcome measures,

256. Restless-Legs Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
     December 16, 2011 - However, severe RLS can have a crippling impact on quality of life. … Except for the limitations on pharmacological therapy imposed by pregnancy, 14 and the use of iron … group in 1995 17 and revised in a consensus conference at the NIH in 2003. 9 The use of standard … We do not know the impact of long-term use of these drugs in children. … We will use the weighted mean difference when studies use the same outcome scale; otherwise standardized

257. - (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease-future_research.pdf
     July 01, 2016 - Question Development and Research Design Considerations. .........................5 Results ...... … Stakeholders identified substantial need for further research on the use of TNF-alpha inhibitors for … One study reported on a patient-reported outcome after surgical resection. … Research Question Development and Research Design Considerations Research questions were developed … Stakeholders identified a substantial need for further research on the use of TNF-alpha inhibitors for

258. Disposition of Comments CER 219 Antipsychotics for the Prevention and Treatment of Delirium (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
     September 03, 2019 - Could the authors please add more language to the methods section on the use of meta analysis. … We clarified in the Data Synthesis section that outcome definition was a key variable for determining … It is probably a predetermined outcome, but a statement of acknowledging the breadth of receptors touched … Many of the studies evaluated the use of antipsychotics more broadly reporting on the inappropriate … For a prevention study, the incidence of delirium would be a crucial outcome and it would be helpful

259. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
     July 10, 2023 - In practice, a clinical diagnosis of GSM is usually made based on the presence of symptoms in a post … , such as women with a history of breast cancer, has relied on expert consensus in the absence of robust … appropriateness of pooling data.24 We will synthesize data using a Hartung, Knapp, Sidik, and Jonkman … Impact of vulvovaginal health on postmenopausal women: a review of surveys on symptoms of vulvovaginal … The Use of Vaginal Estrogen in Women With a History of Estrogen- Dependent Breast Cancer.

260. Rapid Response_Linking Dental Services to Treatment Outcomes for Chronic Kidney Disease: A Rapid Response Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-outcomes-chronic-kidney-rapid-research.pdf
     November 01, 2024 - research conducted by Vindhya Data Science, Inc., under contract to the Agency for Healthcare Research … Research and Quality or of the U.S. … Most AHRQ documents are publicly available to use for noncommercial purposes (research, clinical or … A Meta-Analysis on the Effect of Periodontal Treatment on the Glomerular Filtration Rate of Chronic … Did the review authors use a satisfactory technique for assessing the risk of bias (RoB) in individual