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Showing results for "a research on the use of outcome data".

221. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
     June 22, 2017 - The use of DVT as a proxy for clinically symptomatic PE (intro p. xii); given the documented risk of … However, we have added a sentence to the start of the Introduction reflecting increasing use of early … of clinical outcomes is not focused on clinically important outcomes; (3) the use of network meta-analyses … rather a reflection of the research available. … dvt prophylaxis provides the best outcome-this is not a reflection of the report, but rather a reflection

222. Retention Strategies for Medications for Addiction Treatment in Adults With Opioid Use Disorder: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
     August 01, 2020 - The U.S. Agency for Healthcare Research and Quality, on behalf of the U.S. … Future research should focus on treatment retention as a primary outcome, use standardized measures … Research at FDA, the Office of the Assistant Secretary for Mental Health and Substance Use for the … Strategies The SR16 sought data on adverse events but did not report any, and only one of the eight … Treatment for Opioid Use Disorder: A 2- Year Retrospective Data Analysis.

223. March 2nd Mitigating Racial Bias in Healthcare Algorithms Public Meeting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-2.pdf
     May 15, 2023 - • Utilize social determinants of health and population science big data in research to understand … ET Background • AHRQ received a request from Congress to review the evidence on the potential of … risk of a particular health outcome. … Health & Health Equity to develop a performance evaluation framework on de- identified data (2014-15 … following property: • “If we assign some group a risk of x, the actual outcome incidence rate should

224. Disposition of Comments for Comparative Effectiveness Review 133 Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
     May 27, 2014 - This is a different issue from missing data/attrition/outcome definition since a study could do an … Cannot comment on the appropriate use of statistical methods. … E.g. if a study provided data for 1, 3 and 6 month…only use the 6 month data. … We only had data for the composite outcome in a HR. … We have added a sentence to the table of future research needs suggesting that individual patient data

225. Treatments for Adults with Schizophrenia: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
     September 23, 2016 - controversy and identify needs for future research on the management of schizophrenia. … from the published results of a study, or if we are aware of unpublished data, we will query the authors … If the body of evidence for each intervention and outcome group based on insufficient quality and or … The feasibility of a quantitative synthesis will depend on the number and completeness of reported outcomes … adds a preliminary step of assessing the intervention area for evidence sufficiency based on a

226. Amended Protocol: Maternal and Childhood Outcomes Associated with the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/wic-outcomes-nutrition-protocol-amended.pdf
     October 01, 2020 - WIC participation levels and participant characteristics without outcome data • Descriptive research … The articles will not be excluded based on the study design and outcome at this level. … Data Abstraction and Data Management: We will use a systematic approach to extract all data to minimize … the intervention, outcome measures and the results of each outcome, including measures of variability … We plan to use a mix of methods for summarizing and displaying the types of evidence available on the

227. Amended Protocol: Interventions for Breathlessness in Patients with Advanced Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
     May 19, 2020 - Ideally, the outcome of breathlessness for intervention studies should be a comprehensive assessment … Data Abstraction and Data Management: We will use a systematic approach to extract all data to minimize … We will use standardized forms for data extraction and pilot test them. … in the data abstraction of the articles. … When the body of evidence for a key outcome includes both RCTs and other intervention studies with

228. Research Protocol: Care Interventions for PeopleWith Dementia (PWD) and Their Caregivers (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pwd-care-interventions-protocol.pdf
     February 22, 2019 - We will use a modified PRECIS-2 tool. … Since the PRECIS-2 tool was developed to use during the design phase of a study, this novel use of the … Based on these factors, the overall strength of evidence for each outcome will be rated as: • High … The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation … Primary analysis To what extent are all data included in the analysis of the primary outcome?

229. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - Need to address absence of function as a key outcome measure especially for KQ2. … We appreciate this comment noting that a synthesis of safety data may consider other types of data … We appreciate the concerns about the use of SMD. … of evidence to low based on the small studies (and therefore some imprecision) and the use of run- … May not be used much by the average clinician, but a good resourced for those doing research on DPN

230. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - Need to address absence of function as a key outcome measure especially for KQ2. … We appreciate this comment noting that a synthesis of safety data may consider other types of data … We appreciate the concerns about the use of SMD. … of evidence to low based on the small studies (and therefore some imprecision) and the use of run- … May not be used much by the average clinician, but a good resourced for those doing research on DPN

231. Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
     January 01, 2014 - Intervention There is a lack of IVUS trial data on the influence of operator’s choice of balloon size … For the second topic on imaging diagnostics, there is a lack of data on the use of IVUS, as compared … Intervention There is a lack of IVUS trial data on the influence of operator’s choice of balloon size … Similarly, there is a lack of data on the use of IVUS, as compared with angiography alone, to evaluate … Resource Use, Size, and Duration The reliance on observational data substantially reduces resource use

232. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
     April 21, 2011 - The preponderance of data regarding NPPV as a weaning tool, rescue strategy, and means of preventing … Data Abstraction and Data Management The research team will create data-abstraction forms for the … We will use a checklist to guide the assessment of applicability. … We will use these data to evaluate the applicability to clinical practice, paying special attention … in use, and clinical relevance and timing of the outcome measures.

233. PATIENTSLIKEME (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/clifford.pdf
     May 29, 2025 - use of some of the things that we do in a patient community for researchers and clinicians. … So we have all of this data on the backend in longitudinal data tables. … lithium on the site after they said they were starting to use -- every user of lithium who had ALS … model that was driven by the use of the intervention. … This cost us (inaudible) four months of a research assistant's time, or four months of a head of research's

234. Intermittent Inhalded Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-evidence-summary-corticosteroids-asthma.pdf
     October 01, 2017 - An extension of intermittent ICS therapy is the use of ICS and LABA as controller therapy both on a … treatment of asthma in patients 6 years and older.4 The review focuses on drugs as a class, as described … higher ICS controller dose • Reduces the risk of exacerbations measured as a composite outcome (low … • Reduces: – The risk of exacerbations defined as a composite outcome (moderate SOE) – Rescue medication … a composite outcome (high SOE) – Rescue medication use (low SOE) • Improves asthma control scores

235. Physical Therapy for Knee Pain Secondary to Osteoarthritis Disposition of Comment Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
     November 06, 2012 - the patient-centered outcome all desire, research based on patient-centered outcomes provides patients … These conclusions would serve to justify a PT's use of ultrasound (a passive intervention) instead of … We revised the report focusing on the primary outcome of the review, which is pain. … The ability to walk longer, faster, and on uneven surface is certainly a patient-centered goal and outcome … interventions based on limited data.

236. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
     April 01, 2011 - The research provided little support for their use. … with little data on the treatment of younger children. … For those studies we could use only the pre-post case series data available in the group with autism, … The use of so many and such disparate outcome measures makes it nearly impossible to synthesize the effectiveness … Investigators also failed to report the outcome that was the primary outcome of a priori interest and

237. Medical Therapies for Locally Advanced Gastric Adenocarcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
     February 07, 2025 - We will pilot the data extraction form on a minimum of 4 studies to improve the consistency of extractions … data • Bias in measurement of the outcome • Bias in selection of the reported result Each domain … intended interventions • Bias due to missing outcome data • Bias in measurement of the outcome • … We will use a best evidence approach to address the key questions.16 RCTs at low risk of bias or with … We will assign a rating of Insufficient when the evidence does not permit a conclusion for the outcome

238. Prehospital EMS Blood Transfusion and Fluid Interventions for Hemorrhagic Shock (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol.pdf
     September 24, 2024 - A second reviewer will perform a quality check of the extracted data for completeness and accuracy. … If the included studies for these questions include a variety of designs, we will use the Mixed Methods … Our decision to conduct quantitative syntheses will depend on the number of studies, population, research … We will assign a rating of Insufficient when the evidence does not permit a conclusion for the outcome … Precision is the degree of certainty surrounding an effect estimate concerning a given outcome, based

239. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
     February 01, 2013 - on use of epidural steroid injection for treatment of low back pain and sciatica and to draw conclusions … on whether the study constitutes the only evidence for a given intervention and/or outcome); or inclusion … selection and data extraction had neither a clinically nor a statistically significant effect on the … they use lower-strength evidence for a given SR. … unpublished data or studies that may indicate the presence of publication bias or selective outcome

240. Trauma Informed Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-protocol.pdf
     April 19, 2023 - A Supplemental Evidence And Data for Systematic review (SEADS) portal will be available and a Federal … appropriateness of pooling data.19 We will synthesize data using a Hartung, Knapp, Sidik, and Jonkman … For CQs, we will use a thematic approach, noting the principles and domains of the models and then cross-walking … Based on these factors, the overall strength of evidence for each intervention/comparator/ outcome will … Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a