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effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-evidence-communication_research-protocol.pdf
July 31, 2012 - Precision—“the degree of certainty surrounding an effect estimate with respect to a given
outcome.” … a given outcome; such studies express dispersion around a point estimate of risk, such as a
confidence … searches on the comparative effectiveness of: (1) communication techniques to
promote the use of health … • Measures used
• Source of outcome data
• Results in intervention and control groups
D. … Communicating Data about the Benefits and Harms of Treatment: A
Randomized Trial.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
August 09, 2013 - are available, only outcome data based on the larger number
of patients will be included. … For quality of life (KQ 1g and KQ 2g), this means reporting data on a previously tested
quality-of-life … another risk-of-bias category for other outcomes because the risk of bias can
depend on the outcome … A rating of insufficient will be given when the evidence does not permit a conclusion for the
outcome … Did the patients in different study groups have similar levels of performance on the outcome
of interest
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - Information on the FDA status
and warnings for use the medications considered in this review are provided … Data Abstraction and Data Management
The research team will create data abstraction forms for the KQs … We will use a checklist to guide
the assessment of applicability. … in
use, and clinical relevance and timing of the outcome measures. … Council on Quality of Care and Outcomes
Research: endorsed by the American Psychiatric Association.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
June 15, 2010 - to aid clinicians in their care of patients in whom SSRI use as a first-line therapy for
the index … use
of an SSRI for the index episode. … Abstracted data will include study characteristics (e.g., first author, country of research
origin, … If a particular outcome is shown to have a high risk of publication bias, then the analyses
will be … On some specific reports such as reports requested by the Office
of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-management-of-infertility-comments.pdf
May 14, 2019 - based on
clinical experience and the data. … A reader
should be able to make this interpretation based on data
in the table. … based on
clinical experience and the data. … It also covers a largely academic
discussion of the limitations of the data and how
research in this … evidence base and the rarity
of using a meaningful outcome.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
October 01, 2016 - Neither trial analyzed its data in a way that correctly
made use of the CRT study design, leading to … use of research time and funding
on this topic. … Measures of the use of health
services are important, as are cost implications and data. … ISPN
position statement on the use of restraint and seclusion. … APNA Position
Statement on the Use of Seclusion and Restraint.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
July 01, 2012 - , and trials and observational studies that contained
empirical data on an outcome that corresponded … user and
the intended use of the report. … However, data are not available for all settings, and for
others data are based on a small number of … reporting on
any outcome. … research on the impact of population-level interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
January 01, 2011 - into a set of criteria (attributes and levels):
3
And they use a linear additive value function … subdiscipline of
operations research that explicitly considers multiple criteria in
decision making … Based on their response it is possible to estimate the part-worth
utility of the levels and to … Healthcare. 2011
16
Weighted preference for three antidepressants
17
General remarks on use … Preference data is to be used in conjunction with clinical data.
-
effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
January 01, 2013 - on the basis of similarity of populations, interventions, and outcome measures. … use four levels for grading the strength of a body of evidence. … are about decisions that may be made based on evidence graded one way or another
Requires the use of … Second, a grade of insufficient is also appropriate when evidence on the outcome is too weak, sparse, … Indirect data based on only one study or comparison could also receive a grade of insufficient.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
September 01, 2011 - size for
a clinical outcome. … Peer Reviewer 4 I do not see why the studies on surrogate outcome are rated as “low”
on strength of … to use the data. … In view of this and the recent
FDA bulletin, no further research on terbutaline as a tocolytic is
warranted … Revised accordingly
Peer Reviewer 4 Applicability
and Future
Research
The section on future research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tech-brief-31-mobile-applications-self-mgmt.pdf
May 01, 2018 - of ongoing research, and information on future
research needs. … For each outcome, we extracted data on difference-in-differences, including p-values and
confidence … While the developer has a general privacy policy which
addresses data maintenance, use of cookies, and … dietitian on the use of DID composed of a maximum of three
visits during a maximum period of 2 weeks … rates of
attrition, and a lack of information on how drop-out data were analyzed.
-
effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - based on expected counts of the outcomes of interest, which
were estimated based on historical data. … historical data and estimates critical values based on
a Poisson distribution. … data
on the risk of intussusception after Rotashield vaccination. … the
outcome of facial paralysis. … Presented to the Centers for Education and Research on
Therapeutics—Food and Drug Administration Science
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
December 14, 2010 - The benefits/risks ratio in the long term is also a concern:
effectiveness and safety data are very … of an outcome measure being reported by the trials. … trials, we will abstract data on the
adequacy of the randomization method; the adequacy of allocation … If all studies within a subgroup use the same scale, then the effect
size does not need to be standardized … Further
research is very unlikely to change our confidence on the estimate of effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
May 01, 2012 - on the strength and limits of evidence from research studies about the effectiveness and
safety of a … Research Question Development and Research Design
Considerations
After the second round of prioritization … The outcome would be consensus regarding data to
be collected to address these prevalence and outcome … and outcome measurement tools designed for use in practice-
based research settings and actual clinical … consensus on research priorities in this broad and complex topic area.
31
Conclusions
In this
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
January 27, 2016 - There
is inadequate data on what sub-groups will
benefit for a lot of these RTIs. … use of resistance as the rationale and
appropriate prescribing as the main outcome. … Key Question 2
• The lack of studies that use antibiotic
resistance as a key outcome is cited … as a major limitation of research to
date, and this outcome is given equal
“weighting” alongside inappropriate … and use
outcomes, but data on use
was limited to the some of
the delayed prescribing
studies, where
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - Question Development and Research Design Considerations. .............................11
Ongoing Clinical … Research Question Development and Research Design
Considerations
To develop the future research needs … were not merely due to a lack of studies, but also because of a lack of the
use of study designs, research … Research Question Development and Research Design
Considerations
To develop the future research needs … due to a lack
of studies, but to a lack of the use of study designs and research methodologies and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
June 07, 2013 - Since many
studies provide data for more than one outcome, the
total number of studies included in … the review is
smaller than the sum of the number of studies that
provide data for each specified outcome … on available data. … The data on the effects of age and duration are
indeed difficult to present, especially given the
degree … evidence on the health benefits and harms
of oral contraceptive use and potential use as a cancer
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amendment.pdf
May 02, 2025 - We will pilot the data extraction form on a minimum
of 4 studies to improve the consistency of extractions … intended interventions
• Bias due to missing outcome data
• Bias in measurement of the outcome
• … We will use a best evidence approach to address the key
questions.16 RCTs at low risk of bias or with … If the data are amenable to meta-analysis, we plan to use random-effects models, anticipating
that even … We will assign a rating of Insufficient when the evidence does not permit a conclusion for the
outcome
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research-appendix-c.xlsx
January 01, 2024 - The effect of a nurse manager's authentic leadership intervention on nurses' well-being: A single unit … , evaluate the outcome and reflect on the process
4. … The identified interventions provide a basis for future research to draw conclusions on the effectiveness … data demonstrate a similar trend. … of Nursing Research
Raja, 2023 Time series "To estimate the causal effects of minimum ratios on hospitals
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
May 01, 2015 - The absence of data on the natural
history of untreated ankyloglossia further promulgates
uncertainty … of the frenulum with age and use.1 However, there are no
prospective longitudinal data on the congenitally … , and baseline and outcome data on constructs
of interest. … Because of the
paucity of available data on other feeding outcomes, this
entire research question represents … Future research is needed on a
range of issues, including prevalence and incidence of
ankyloglossia