-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol-2021_0.pdf
January 01, 2021 - Systematic reviews typically abstract a small number of data elements pertinent to the scope of
the … Hence, there is a need for a single source that provides up-to-date,
detailed, comprehensive data on … to
determine future research priorities; (3) encourage researchers to adopt standard data elements … in
research and reporting; (4) serve as a source for clinicians seeking information on effectiveness … from measurement),
and the percent of missing primary PTSD outcome data in each of the arms of the
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - The review also will highlight areas of controversy and identify needs for future
research on the management … 3.3 Was information on intervention status unaffected by knowledge of the outcome or risk
of the outcome … Risk of bias judgment
Bias due to
missing data
5.1 Are outcome data reasonably complete? … unlikely to be selected, on the basis of the results, from...
7.1multiple outcome measurements within … to which the included
studies for a given outcome or comparison have
a high likelihood of adequate
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
April 09, 2020 - We will also use items from the
NHLBI Tool focusing on the adequacy of descriptions of study eligibility … We will also use items from the NHLBI Tool focusing on the
adequacy of descriptions of study eligibility … “core outcome set” that was published in 2015 for research on breast
reconstructive surgery.33,34 Core … outcome sets are agreed minimum sets of outcomes that should be
reported in research in a given topic … Development of a core outcome set for research and audit
studies in reconstructive breast surgery.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dot-plots-methods.pdf
October 01, 2021 - is intended for display of data from an individual study; it is not designed
for use with pooled data … a review on opioids for chronic pain.5 The statins review focused on
dichotomous outcomes; for the … Data dictionary for Table 1A
Variable Name Description
Outcome Outcome name
No. of Trials Number of … Data dictionary for Table 2A
Variable Name Description
Outcome Outcome name
No. of Trials Number of … Data dictionary for Table 3A
Variable Name Description
Outcome Outcome name
No. of Trials Number of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
October 17, 2012 - Given the increasing use of meditation across a large number of conditions, examining the effects of … Expected Use of the Report
A rigorous systematic review of meditation in addressing the effects on … We will use a systematic approach for extracting data to minimize the risk of bias in this process. … Commentary on the AHRQ report on research on meditation practices in health. … Use and avoidance of continuity
corrections in meta-analysis of sparse data.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/dot-plots-methods.pdf
October 01, 2021 - is intended for display of data from an individual study; it is not designed
for use with pooled data … a review on opioids for chronic pain.5 The statins review focused on
dichotomous outcomes; for the … Data dictionary for Table 1A
Variable Name Description
Outcome Outcome name
No. of Trials Number of … Data dictionary for Table 2A
Variable Name Description
Outcome Outcome name
No. of Trials Number of … Data dictionary for Table 3A
Variable Name Description
Outcome Outcome name
No. of Trials Number of
-
effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
January 01, 2013 - control for such intermediate variables could block some of the effect of the treatment on the outcome … use of instrumental variables. … effect of the instrument on the treatment, and the effect of the instrument on the outcome, can together … be used to essentially back out the effect of the treatment on the outcome. … Consider the effect of missing data on analyses.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - confidence that the evidence in the review reflects the true effect of a given intervention on an
outcome … For example, studies in a review may use a variety
of scales to measure the same outcome, and those … Selective
Analysis
Reporting
Outcome data are reported but they are based
on the most favorable … use a
quantitative assessment that investigates the “missingness” of outcomes data from small studies … The impact of outcome reporting bias in
randomised controlled trials on a cohort of
systematic reviews
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
November 30, 2014 - , we may use their abstracted study, population, and outcome data, which will be verified
by a trained … We will use data provided by the systematic review to assess
strength of evidence for results that lack … , blinding of outcome assessment, incomplete outcome data, selective
outcome reporting, and other sources … Since the use of a validated risk of bias
tool is an inclusion criterion, we anticipate consistency … studies, we plan to pool data from multiple studies based on treatment-
outcome comparisons only.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
January 01, 2012 - It may not make sense to combine a
surrogate outcome (e.g., lung function) and quality of life on the … Fifteen of the approaches are data driven, but 3 of the 16 may also use simulation while one
approach … for
organizing outcome data on the same scale.
41
This approach needs individual patient data. … The choice of a particular approach depends on the decision to be informed, the
available data, and … Multi-criteria Clinical Decision
Support: A Primer on the Use of Multiple Criteria
Decision Making
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - Systematic reviews typically abstract a small number of data elements pertinent to the scope of
the … Hence, there is a need for a single source that provides
up-to-date, detailed, comprehensive data on … other cross-study comparisons; (2) help identify research
gaps to determine future research priorities … Due to the nature of the project, a
portal for submission of Supplemental Evidence And Data for Systematic … Did the study use adequate methods for handling missing data?
k.
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effectivehealthcare.ahrq.gov/sites/default/files/exposure-definition-and-measurement_chapter-4.pptx
January 01, 2013 - to have an effect on the outcome. … to influence the validity of the information that is collected depending on the nature of the data. … sources of data, assumptions about actual use are still inherent in the use of these data for determining … influence of other exposures on the outcome. … /intervention and outcome of interest, awareness of the level of detail on the exposure in a dataset
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - A 2007 study on Efficacy and Comparative Effectiveness of
Off-label Use of Atypical Antipsychotics reviewed … , laboratory data, and time to disease
recurrence; for the effectiveness, we will report outcome measures … Adverse events
associated with on-label use of the atypical antipsychotic medications will be summarized … data on the adequacy of the randomization
method; the adequacy of allocation concealment; maintenance … On some specific reports such as reports requested by the Office
of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
December 01, 2010 - Work Plan for Methods Research on
Methods Research Report
Developing and Testing a Tool for … attention on the applicability of research. … First, training in
research methods, as well as in the use of the tool, is essential. … • A study in which data are collected at a series of points in time on the same population to
observe … • A study in which data are collected at a series of points in time on the same population to
observe
-
effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
January 01, 2013 - of the outcome. … The analysis can be repeated using these different definitions of the outcome, which may shed light on … It may be possible to acquire multiple data sources for a single analysis and to use additional data … be formed with a clear awareness of the limitations of the data and the nature of the problem. … they can be tested, and discussed the use of alternate data sources.
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effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
October 30, 2012 - This research
serves as a cautionary tale for the creation
and use of composite endpoints. … Outcome Definition and Measurement
In this section we focus mainly on the use of
standard instruments … In such instances, use
of the same or similar data sources and equivalent
outcome definitions to the … Conclusion
Future Directions
Increased use of EHRs as a source of data for
observational research, … of the effect of treatment on the main outcome of interest.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
August 24, 2011 - a general sense of the relative use of each
method in the U.S.
2
A 2002 review of labor pain management … on the use of nitrous oxide. … measure of
an outcome listed in the PICOTS
Relevant outcomes must be extractable from data
presented … To ensure comprehensive retrieval of relevant research into the use of
nitrous oxide for pain relief … Each key outcome on each comparison of interest will be given an overall
evidence grade based on the
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01_0.pdf
May 01, 2005 - underlying research).”14
Because of inconsistency and potential misunderstanding in the use of the … to a
given outcome, based on the sufficiency of sample size and number of events.24 Both GRADE33 … Choice of Outcome Measures
The use of valid and reliable outcome measures reduces the likelihood of … In the category of missing data, on the other hand, the
direction of bias depends on whose data are … For example, if an outcome is unaffected by blinding,
then the unconsidered use of a blinding “rule”
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
May 01, 2005 - underlying research).”14
Because of inconsistency and potential misunderstanding in the use of the … to a
given outcome, based on the sufficiency of sample size and number of events.24 Both GRADE33 … Choice of Outcome Measures
The use of valid and reliable outcome measures reduces the likelihood of … In the category of missing data, on the other hand, the
direction of bias depends on whose data are … For example, if an outcome is unaffected by blinding,
then the unconsidered use of a blinding “rule”
-
effectivehealthcare.ahrq.gov/sites/default/files/ch-7-user-guide-to-ocer_130129.pdf
March 29, 2012 - has a causal
effect on the outcome. … of the variable at a
later time (C
1
) is on the causal pathway between
treatment and outcome. … an effect of treatment (A
0
) on
the outcome (Y
1
). … on the
researcher’s knowledge, the data quality, and the
number of covariates. … Discussion of research using propensity-
score matching: comments on ‘A critical appraisal
of propensity-score