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Showing results for "a research on the use of outcome data".

161. Quantitative Synthesis Chapter 3. Choice of Statistical Model for Combining Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
     February 01, 2018 - of outcome ► Potential bias • Do not choose a model based on the significance level of a heterogeneity … rare binary outcome data.11 ► This model assumes that outcomes of each trial follow a binomial distribution … A simulation study of the impact of the use of vague prior distributions in MCMC using WinBUGS. … • For study-level aggregated binary data and count data, use of a generalized linear mixed effects … A simulation study of the impact of the use of vague prior distributions in MCMC using WinBUGS.

162. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
     September 08, 2011 - This figure depicts the potential impact of use of procalcitonin on both intermediate outcomes and … o Prospective vs. retrospective o Use of independent outcome assessor o Additional elements … o Did the analysis of outcome data incorporate a method for handling confounders such as statistical … Stolz A, Tamm M. Discriminate use of antibiotics for exacerbation of COPD. … In the section of the report focusing on research gaps, we will emphasize unresolved questions that

163. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disabilities-quality-improvement-outcomes_research-protocol.pdf
     August 03, 2011 - The sections on population, outcome measures, and quality measurement research factors below provide … They are a component of a research analysis plan. … tool, type of quality improvement research for which the tool was used, data sources, and end users … Data Synthesis We will use qualitative techniques to synthesize the literature. … Research to establish the validity and reliability of the outcome measures with regard to relevant

164. Er r or Rate Reduction Regarding Lower Limb Prosthesis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
     March 16, 2017 - Level 1: Has the ability or potential to use a prosthesis for transfers or ambulation on level surfaces … for determining the outcome of the matching of a patient to a specific LLP, and how to best measure … What functional outcome measurement tools used to assess adults who use a LLP have been evaluated in … In adults who use a lower limb prosthesis, how do the relative effects on ambulatory, functional, and … data on excluded populations).

165. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
     September 01, 2012 - ................. 10 Research Question Development and Research Design Considerations ............. … Availability of data/ability to recruit Good; PCD is a rare disease but use of RCT or registry data … Availability of data/ability to recruit Good; PCD is a rare disease but use of RCT or registry data … Research Question Development and Research Design Considerations The EPC transformed the final list … Availability of data/ability to recruit Good; PCD is a rare disease but use of RCT or registry data

166. Diabetes-Behavior-Programs Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
     June 05, 2014 - , blinding of outcome assessment, incomplete outcome data, selective outcome reporting, and “other” … sources of data), and a categorization of the overall risk of bias. … methods, duration, and so forth; they will not be given any data on outcome results. … [<70%] outcome data). … We will assess directness of the evidence (direct or indirect) on the basis of the use of surrogate

167. Ch 2-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
     January 01, 2011 - information to guide the selection of an appropriate study design for a research question of interest … User’s Guide of the research project. … (e.g., a drug/device or disease registry) may offer advantages such as availability of data on covariates … On the evaluation of drug benefits policy changes with longitudinal claims data: the policy maker’s … Influence of run-in period on incidence of NSAID use in European population in the SOS project.

168. Fiber Intake and Laxation Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-protocol.pdf
     August 15, 2023 - To ensure a focus on the effect of fiber, the review excludes review of combinations of fiber and other … of 1 week following the end of a prior intervention period (i.e., excluding data from the equivalent … We typically use a threshold for the prediction score of the unscreened citations of 0.40 (this threshold … The structure of the data synthesis (Results section) will depend in part on the characteristics of … Conducting research on diet-microbiome interactions: A review of current challenges, essential methodological

169. Ch 9-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
     September 21, 2012 - 129 Abstract The feasibility of a study often rests on whether the projected number of accrued patients … specifying a measure of data variability. … the standard deviation of the outcome in each trial arm; when the outcome is the occurrence of an … A basic study design for expedited signal evaluation based on electronic healthcare data. … Multiple imputation for missing data in epidemiologic and clinical research: potential and pitfalls

170. Treatment of Stage I-III Squamous Cell Anal Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/anal-cancer-protocol.pdf
     September 26, 2023 - appropriateness of pooling data.16 We will 11 synthesize data using a Hartung, Knapp, Sidik … We will present the overall certainty or strength of the evidence for each outcome according to a … A., & American Joint Committee on Cancer Expert Panel on Cancers of the Lower Gastrointestinal, Anus … advanced anal cancer: results of a phase III randomized trial of the European Organization for Research … We will present the overall certainty or strength of the evidence for each outcome according to a

171. Disposition of Comments: Technical Brief No. 38_Automated Entry Patient Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-38-chronic-conditions-comments.pdf
     March 01, 2021 - albeit based on a wide variety of research studies with varying quality. … along with the outcome would enhance interpretation of these data as a patient with NYHA class 1 HF … This trial did find a benefit of PGHD on a surrogate outcome, but the trial was at high risk of bias … The use of mHealth creates a socio-technical system. … Brief notes that little underlying research isolates the effects of a connected device alone on health

172. Disposition of Comments Report for Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma-Cell Dyscrasias (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
     August 23, 2012 - Peer Reviewer #2 Results One conclusion of the study on the use of FLC for assessing risk of MGUS … However there was a paucity of such comparative data in these categories, indicating a future research … This underscores their main point that there is a paucity of high-quality data on the comparative effectiveness … that the consequence was the demonstration of a paucity of high- quality data on the one hand but a … body of data supporting the use of the SFLC assay for clinical use in general.

173. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
     July 19, 2023 - enrolled a consecutive or random sample, whether the data are not based on a retrospective case-control … limitations: The extent to which studies reporting on a particular outcome are likely to be protected … particular outcome; graded as consistent, inconsistent, or unknown (in the case of a single study) … • Precision: Describes the level of certainty of the estimate of effect for a particular outcome, … We will use these data to evaluate the applicability to clinical practice, paying special attention

174. Mental-Illness-Adults-Prisons Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_executive.pdf
     August 01, 2013 - on a review of the data abstracted, we narratively summarized any patterns reflected from these factors … More research is needed to better assess the impact of provider type on treatment outcomes. … Below we outline research gaps based on the PICOS (population, intervention, comparator, outcome, and … More research is needed on the effectiveness of MTC interventions, pharmacologic therapy, and cognitive … The use of telepsychiatry within forensic practice: a literature review on the use of videolink.

175. Making Healthcare Safer IV Rapid Review: Patient Monitoring Systems To Prevent Failure To Rescue (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-rapid-review.pdf
     December 01, 2024 - Other areas of research not in the scope of this rapid review include attention on enhancing the ability … The risk of bias assessments focused on the main outcome of interest in each study. 2.5 Data Synthesis … on reducing telemetry use). … , South Korea, and the Netherlands) examined the effect of these interventions on the outcome of transfer … and Future Research Future efforts should focus on improving the quality of research in this area

176. Adverse Effects of First-Line Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
     February 07, 2018 - Post-hoc and subgroup analyses of included studies will be considered when they provide data on the … given the identified limitations.12 Data Synthesis - For each KQ, we will create a set of detailed … Synthesis of data will be based on the pharmacologic class named as the intervention and comparator, … studies report the outcome. … for rare event outcome: a simulation study.

177. Continuous-Outcomes-Quantitative-Synthesis Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
     March 01, 2011 - enough data to calculate mean difference based on both options 1 and 2, use the estimate with the … are based on the mean of the variable of interest, for example, a clinical outcome and a measure of … variety of instruments on different scales to assess the same outcome. … outcome) on the combined estimate. … Otherwise, use either option 1 or 2 based on the available reported data of the included study.

178. Evidence Map on Home and Community Based Services (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-map-hcbs-protocol.pdf
     July 27, 2023 - Describe the available research on the effectiveness of person-centered HCBS interventions, for adults … Describe the gaps that exist in the current research. a. … Data Collection: A. … We will use a semi-structured interview guide to guide the group conferences. … Data Collection: A.

179. Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
     January 01, 2012 - Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the … A Framework to Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research … SR has explicitly addressed a stated outcome/aim (or more than one outcome/aim) of the proposed research … Most of the current literature on improving the use of SRs in research study design has arisen from … Implications: very little data on use of oral steroids, which is most likely to be the type of steroids

180. Web Interactive Presentation of EPC Reports: A Foray Into Interactive Reports (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-web-interactive-presentation.pdf
     September 01, 2019 - We used data from a systematic review we conducted through the Agency for Healthcare Research and Quality … The stakeholders were satisfied with the functionality of the tool, and commented on its ease of use … on Specific Outcomes For users interested in a specific outcome (e.g., satisfaction) or a specific … with data for this outcome (Figure 3). 6 Figure 3. … received, we envision a rich set of use cases for interactive reports.