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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
October 01, 2022 - makers and funders of research … • Levetiracetam may cause seizure freedom in some patients, but data on other
medications (topiramate … the Evidence-based Practice Center (EPC) program
of the Agency for Healthcare Research and Quality … or seizure types, no included data on the cost of treatments, and the variability
of surgical interventions … In general, evidence on the management of infantile epilepsies is
weak, and better-quality research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/recombinant-factor-viia_clinician.pdf
October 01, 2010 - increased despite limited comparative data
on its effectiveness and safety. … However,
in recent years the off-label use of rFVIIa has increased
in the hospital setting to prevent … Utilization and Clinical Data on In-Hospital, Off-Label Uses of
Recombinant Factor VIIa
1 In January … The research questions and the
results of the report were subject to expert input, peer review, and … unit of analysis was any hospital “case” of rFVIIa use—defined as any
application during a patient hospitalization
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-disposition-comments.pdf
August 29, 2023 - to the table could be of use perhaps. … I liked it and the use of the appendix
to put things into a place where people can take a deep dive. … should be emphasized as this data is based on
the inclusion of two poor quality studies (which, when … ASTRO expressed a
desire to have additional overall
analyses based on combining data
across RCT treatment … No cost analysis is done - on policy it is key to understand
that SBRT bills at a higher rate so use
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
June 01, 2010 - The Biomedical Research Workgroup made a recommendation that
further research on 17-OHP be supported … Question 6
What is the effect of health systems and provider factors on the use of progestogens for … and enter them on the data abstraction forms. … Impact of the recent randomized trials on the use of
progesterone to prevent preterm birth: a 2005 follow-up … On some specific reports such as reports requested by the Office
of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/screening-counseling-interventions-executive-summary.pdf
April 01, 2025 - The evidence on the impact of implementation strategies on inequities
in the delivery of recommended … for more research on the
impact of strategies to implement recommended screening and counseling
interventions … We abstracted data on characteristics of study populations, settings, clinical
interventions, potential … information on health risks of alcohol and cannabis use more often than
providers in the technology … Survey on Drug Use and Health. 2024.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
July 01, 2012 - ) think about synthesizing
data on the performance of medical tests when the reference standard is imperfect … when outcome information (usually on long-term outcomes)
exists, and the measured patient outcomes … A clinically relevant example is the use of prostate-specific antigen (PSA) to detect prostate
cancer … AHI>15 events/hour
These data are on a subset of studies from the systematic review used in the … we have virtually
no empirical data on the merits and pitfalls of methods that mathematically adjust
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - We will develop a search strategy for
MEDLINE, accessed via PubMed, based on an analysis of the medical … comparison for each outcome. … On some specific reports such as reports requested by the Office
of Medical Applications of Research … that did not specify the adjunctive medications, such as those stating use of “any oral hypoglycemic” … o We did not include data on total cholesterol or other measures of glycemic variability.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
November 01, 2020 - • Use of the machine learning classifier resulted in a small to moderate estimated time
savings … Performance was similar using
the training data and on the simulated updates. … to use SVM for the remainder of the analyses
on each topic because its performance was equivalent to … were more imbalanced (i.e., a lower proportion of studies included) than in the training data. … The use of text word-only searches is important for conducting LSRs because of the
lag between entry
-
effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Any investigator or funder of research will be able to use the AHRQ Healthcare
Horizon Scanning System … repair (MitraClip) for treatment of mitral
regurgitation
Moderately high
Discussion
Research activity … The panel also voted 12-0 on a reasonable
assurance of safety, but 6-7 against on a reasonable assurance … research perspective commented, “Long-term
follow-up data that support the safety and efficacy of Watchman … The following available cost information is based on inpatient use of the SynCardia TAH-t.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
December 09, 2009 - Data abstractions will be reviewed for accuracy by
a second member of the team.
D. … of studies, we will use predefined criteria based on
those developed by the US Preventive Services … use of non-pharmacological treatments, we will consider quantitative analysis (meta-
analysis) of data … methods of the EPCs, which use a
revised version of the approach devised by the GRADE working group … On some specific reports such as reports requested by the Office
of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemophilia-dental-rapid-response.pdf
July 01, 2024 - research studies or systematic reviews that
evaluated the effect of dental care on hemophilia treatment … We chose 1960 to cover a breadth of potential use of clotting factors in the treatment for hemophilia … Our review of the search results focused on identifying primary research studies, SRs, and clinical … Study Selection
Study eligibility was based on the population, intervention, comparator, outcome(s) … the use of
patient pamphlets.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/musculoskeletal-complaints-tests-children_research-protocol.pdf
September 29, 2010 - Data on children are few,12 but pediatric data suggest an estimated
incidence of SLE to be 0.36 per … treatment may lead to an improved outcome.23
To support a diagnosis of either JIA or SLE, the ideal … • Any language
Population • The study provides separate data for a population consisting of
children … Data Collection
Data will be abstracted by a single reviewer using a standard data extraction form … On some specific
reports such as reports requested by the Office of Medical Applications of Research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/febrile-infants-diagnosis-management_executive.pdf
March 01, 2012 - of the febrile infant and to identify needs for
future research. … for
WBC (AUC range: 59.0 percent to 69.0 percent).43,44,47
The use of CRP demonstrated higher overall … The reported data on the presence of HSV in febrile infants
3 months or younger was scarce. … percent) due to small counts.78-80
The data on comparison of the prevalence of SBI between
virus-positive … In the absence of better data on harms
and the costs of diagnostics and therapeutics or improved
positive
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_clinician.pdf
July 01, 2016 - :
Current State of the Evidence
Focus of This Summary
This is a summary of a systematic review evaluating … The strength of evidence for most of these procedures and
surgeries was rated insufficient, as the data … clear guidance about how to use systems-level interventions. … Further research may change
our confidence in the estimate of effect and may
change the estimate. … on the long-term outcomes after PPH management
are very limited.
�� Only a few of the studies included
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-executive-summary.pdf
December 01, 2023 - • We found an unexpectedly large volume of research on violence and trauma
relative to other potential … • For outcome domains, depression/other mental health outcomes represented a
large proportion of the … ’s Office of
Research on Women’s Health, the National Heart Lung and Blood Institute, the National … The methods we selected for this review provided a detailed map of the research
connecting racism … expertise or interest—
gain a wider perspective on the breadth of literature within which their specific
-
effectivehealthcare.ahrq.gov/sites/default/files/15_crosscutting_potential_high_impact_2012-12-11.pdf
January 01, 2012 - Any investigator or funder of research will be able to use the AHRQ Healthcare
Horizon Scanning System … personal monitor,
and a Bluetooth-enabled data device such as a cell phone comprise the system. … the theory underlying the intervention
than on available trial data. … , citing a lack of data at this point and uncertainty about its true impact on adherence. … the sizable burden of inappropriate ED use on both health care costs and patient
health outcomes,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - The report focused on use of nonopioids in
patients with chronic pain and addressed the following Key … Additional research is needed on
longer term followup, quality of life, direct comparisons of nonopioid … the strength
and limits of evidence from research studies about the effectiveness and safety of a clinical … whole on the state of the
science. … with opioid use disorder
• For KQs 1c, 2b: Subgroups of the above patient populations as defined by
-
effectivehealthcare.ahrq.gov/sites/default/files/interventions-horizon-scan-high-impact-1306.pdf
June 01, 2013 - Any investigator or funder of research will be able to use the AHRQ Healthcare
Horizon Scanning System … the potential of the intervention more than on
available data thus far. … , citing a lack of data at this point and uncertainty about its true impact on adherence. … systems perspective commented that “the use of this intervention on a national scale will support … the past 2
years, as data begin to accumulate about the impact on outcomes of geriatric-centered ED
-
effectivehealthcare.ahrq.gov/sites/default/files/cultural-competence_disposition-comments.pdf
January 01, 2020 - interventions and
outcome measures. … As our report recognizes, having data
on disparities should be a precursor to
creating interventions … However, evidence for the
best way to collect data is beyond the
scope of this review. … ,
CEO of
Hepatitis
Foundation
International
LGBT Data on Gender and Sexual Minority Populations … multiple minority
groups represents a more efficient use of scarce resources and the
application of
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting_hi_impact.pdf
January 01, 2012 - Any investigator or funder of research will be able to use the AHRQ Healthcare Horizon Scanning
System … the part of clinicians to review data and shift patient management as a result … data
on the smart pill. … be trained on the use of the system; and clinicians or other staff members would need to
analyze the … significant amount of data the system captures about each patient, which would place new
demands on