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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
May 29, 2025 - "
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SOE:&High&(ACEI&vs. … ,$the$clinical$relevance$of$which$needs$to$be$tested$by$ad"hoc$outcome$studies.$
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supporting$the$use$of$azilsartan$for$improvement$in$cardiovascular$outcomes … quantitative$
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Rate&of&use&of&a&single
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_research-2012.pdf
January 01, 2012 - Do one or more members have a preferred, pre-determined outcome? … Use a “parking lot” designated on a flip chart to capture issues that need to be
addressed, but which … Use a “parking lot” to capture issues that need to be addressed, but which are not the
focus of the … Use a “parking lot” to capture issues that need to be addressed, but which are not the
focus of the …
Write it down, and hang it on the wall, or use a visual electronic tool that
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
November 01, 2012 - na
ly
si
s
15
Although symptom scales are widely used in research
studies, their use in clinical … We found no RCT data on the comparative benefits or
harms of dopamine agonists and anticonvulsant alpha … data on nonpharmacologic
interventions or the effect of patient or RLS characteristics
on outcomes … Methodological
Issues Findings Research Needs
Outcome measures • It is not clear if the degree of benefit … Impulse
control disorders with the use of dopaminergic agents in restless
legs syndrome: a case-control
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
April 01, 2016 - Most KIs could see a use for a rapid review, in particular for guideline
development focused on narrow … End-users liked to see the outcome data,
methodological quality, and strength of evidence summarized … , the use of evidence and summary tables, strength of evidence assessments, and future
research recommendations … A perceived use for a rapid response was to validate the need for future research or an
evidence synthesis … Improving the use of research evidence in
guideline development: 8.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
June 01, 2012 - This can be due to the lack of reliable prevalence data or a lack of long-term outcomes data. … data on the analytic validity of a genetic test, the external proficiency testing program carried out … term=12181099
DNA-Based Assays
Analyze the DNA itself
Use a variety of sample sources (e.g., blood … Rather, testing based on family history is the paradigm that is recommended to guide the use of BRCA … intended use of the test.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
June 01, 2012 - This can be due to the lack of reliable prevalence data or a lack of long-term outcomes data. … data on the analytic validity of a genetic test, the external proficiency testing program carried out … term=12181099
DNA-Based Assays
Analyze the DNA itself
Use a variety of sample sources (e.g., blood … Rather, testing based on family history is the paradigm that is recommended to guide the use of BRCA … intended use of the test.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0495_05-24-2013.pdf
January 01, 2013 - for a full systematic review due to the limited data available at
this time; however, it will be considered … and posted
on the EHC Program Web site. … (For more information,
seehttp://effectivehealthcare.ahrq.gov/index.cfm/submit-a-suggestion-for-research … A variety of techniques may be used based on treatment strategy and location of
metastases. … and outcomes of
interest in order inform future research in this area.
-
effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
January 01, 2012 - Any investigator or funder of research will be able to use the AHRQ Healthcare
Horizon Scanning System … use and costs of any health care technology. … Methods
As part of the Healthcare Horizon Scanning System activity, a report on interventions deemed … FDA approved the drug on July 17, 2012, on the basis of two
completed, phase III trials. … on this outcome have not been reported.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
September 01, 2015 - The search strategy and results of the searches are recorded
on a standardized data entry form that … Start of new trials or announcement/publication of late-phase data on the topic
3. … Covers future industry
trends, key industry developments,
research and development of drugs and
pharmaceuticals … Purpose is to advance clinically-relevant
knowledge of cancer, and improve the
outcome of prevention … meeting presenting
research on the use of radiology
in medicine
X X X X
54 San Antonio Breast
-
effectivehealthcare.ahrq.gov/sites/default/files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
September 01, 2015 - The search strategy and results of the searches are recorded
on a standardized data entry form that … Start of new trials or announcement/publication of late-phase data on the topic
3. … Covers future industry
trends, key industry developments,
research and development of drugs and
pharmaceuticals … Purpose is to advance clinically-relevant
knowledge of cancer, and improve the
outcome of prevention … meeting presenting
research on the use of radiology
in medicine
X X X X
54 San Antonio Breast
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-revised-comments.pdf
December 29, 2020 - Data
on the adverse events associated
with use of opioids are
summarized in the
Introduction/Background … It provides a specific
outcome, versus a generic use of “not
effective.” … of the data. … There is mention that the few studies
that looked at long-term opioid use were
based on claims data … of the data.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-executive-summary.pdf
November 01, 2024 - The Effect of Protein Intake on
Health: A Systematic Review
Executive Summary
Main Points … • A notable research gap regarding the impact of dietary protein intake on bone
health in children … The variety of outcome measures, the differences in dietary protein intake
levels, and sparse outcome … of chronic diseases, diverse outcome measurement
methods with inherent limitations, the absence of … The Effect of Protein Intake on Health: A Systematic Review. Systematic
Review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
September 01, 2021 - • Research is needed to determine the benefits and harms of other interventional
procedures addressed … based on mean age of over 65 years in the trials. … Data on harms were relatively sparse and
inconsistently reported. … Data on long-
term (≥1 year) outcomes was relatively limited. … , and additional research is needed to determine
benefits of harms (Table A).
-
effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
January 01, 2012 - Any
investigator or funder of research will be able to use the AHRQ Healthcare Horizon Scanning System … use and costs of any health care technology. … Results
The table below lists the nine topics for which (1) preliminary phase III data on drug topics … antiobesity drug available for long-
term use in the United States and for use in adolescents. … on this outcome have not been reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-synthesizing-evidence-improve.pdf
July 01, 2020 - These reviews focus on a variety of clinical, behavioral, economic, and
other issues. … of the overall body of evidence
◆ Grading the Strength of a Body of Evidence When Assessing Health … Care Interventions for the Effective Health Care Program of the Agency
for Healthcare Research and Quality … EPC Program also supports research on complex methodological issues in systematic evidence reviews. … a review on treatments
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
July 06, 2015 - synthesis of data on the
comparative effectiveness and associated harms of ACEIs or ARBs, or the combination … , 5) studies that followed patients
for a minimum of 6 months, and 6) reported efficacy data on pre-specified … for RCTs or observational studies of at least 1000 patients, and 5) reported
data on pre-specified … The use of ACE inhibitors was associated with
hypotension. … The use
of ACE inhibitors was associated
with hypotension.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
May 22, 2025 - Data were insufficient to assess the effect of co-occurring disorders on treatment effects. … To synthesize data on effect modifiers of effectiveness and harms when available. … Inconsistency with the outcome of suicide attempts
Indirectness of evidence when extrapolating from rigorous … Common factors responsible for outcome? … Research on benefits and harms of hospitalization
Qualitative research – treatment burdens
Rigorous
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_executive.pdf
June 01, 2013 - A negative mean change
indicated a decrease in outcome measure (e.g., BMI). … Further research is very unlikely to change our
confidence on the estimate of effect. … We found no data on long-term adverse events of bariatric
surgery in diabetes or IGT patients in our … Future Research
Future research should focus on long-term outcomes of
bariatric surgery in U.S. patients … Long-term followup of the research subjects, if funded,
could add to our knowledge base on the effects
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/organization-cancer-care-disposition-comments.pdf
June 20, 2023 - on EMR data if not also numeracy of
clinical leaders for being able to generate, analyze, or act on … Finally, they
report on the use of a standardize method for review of literature, including
use of … perspectives on each stage of the process likely strengthened the rigor
and reliability of our research … whether a potential outcome of
this report might be the generation of scientific and/or publication … I would
encourage the study team to use a more deductive approach to identify
themes based on the Integrated
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0255_06-25-2010.pdf
January 01, 2010 - For patients having a stent implantation, what is the comparative effectiveness of
using intravascular … The most commonly used techniques with a variety of
applications are the intravascular ultrasound (IVUS … Clinical consultation on this topic indicates that there is emerging data on different techniques
for … http://effectivehealthcare.ahrq.gov/index.cfm/submit-a-suggestion-for-research/how-are-research-topics-chosen … /�
http://effectivehealthcare.ahrq.gov/index.cfm/submit-a-suggestion-for-research/how-are-research-topics-chosen