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Showing results for "a research on the use of outcome data".

1281. Executive Summary - Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
      January 01, 2023 - on the impact on opioid use were not reported or evidence was insufficient to draw conclusions … The purpose of the systematic review is to evaluate the evidence on benefits and harms of cannabinoids … impact on the use of opioids for chronic pain, were not reported in the RCTs. … As the strength of this evidence is mostly low, more data are needed to confidently recommend cannabis … Clinical outcome data of chronic pain patients treated with cannabis-based oils and dried flower from

1282. Comparative Effectiveness Review No. 258_Diagnostic Errors in the Emergency Department: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/diagnostic-error-executive-summary.pdf
      August 01, 2023 - increased availability/intensive use of diagnostic technologies or other factors … 5 on a 6-point Likert scale. … The Swiss study assessed deaths as an outcome among admitted patients and found a 2.3-fold increase … Future research should emphasize areas in which data are suboptimal or lacking. … More research is needed on the burden of diagnostic errors and harms related to diseases with less immediate

1283. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
      January 01, 2013 - Question Development and Research Design Considerations ................................ 13 Results … Research Question Development and Research Design Considerations We transformed the final list of … Research Question Development and Research Design Considerations We transformed the final list of … The reliance on observational data substantially reduces resource use and increases the feasibility … of Stakeholders, Researchers, and Funders Research Question Development and Research Design Considerations

1284. Defining an Optimal Format for Presenting Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
      January 01, 2019 - other secondary research reports that are based on data from multiple sources, such as decision or … They are frequently based on systematic reviews of the relevant literature and use cost-utility analysis … The concept of a stand-alone document on future research needs is probably new to most of the individuals … 2002 Health Policy 15248937 A pilot study on the use of decision theory and value of information … 'routine' data in randomised controlled trials 2003 Health Econ 14984281 The use of decision models

1285. Horizon-Scan Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
      December 01, 2011 - The search strategy and results of the searches are recorded on a standardized data entry form that … development or on the cusp of diffusion because more data will likely have accumulated to use in the … Are there new data that have shed new light on an intervention, such as a. … Covers future industry trends, key industry developments, research and development of drugs and pharmaceuticals … Purpose is to advance clinically-relevant knowledge of cancer, and improve the outcome of prevention

1286. An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_disposition-comments.pdf
      December 01, 2011 - have data on the effects of each approach. … They may be comingled by necessity depending on the data sources examined, but WW is frankly a fading … The significant number of pages in the report devoted to the data on other observational management … Our future research recommendation was based on the assumption that the key question is a question of … of the data on patient outcomes from observational cohorts of AS.

1287. High-Cholestorol-Medicines-Update Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_executive.pdf
      February 01, 2014 - the true effect and further research may change our confidence in the estimate of the effect and may … A comparison-outcome pair with high SOE was one with low risk of bias, directness, consistency, and … study personnel (performance bias), for not reporting the blinding of outcome assessors (detection … comment on the tolerability of or persistence with the regimen, given the lack of data and short trial … use of these combinations.

1288. Arthritis-Psoriatric Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
      April 01, 2012 - Analytic Framework Figure A lays out the analytic framework that guided the research. Figure A. … Hand searches were conducted on the Center for Drug Evaluation and Research (CDER) database of the … A senior reviewer evaluated the completeness of each data abstraction. … trials, where adverse events were not the primary outcome. … Overall, the data are quite limited and the evidence is insufficient to draw firm conclusions on comparative

1289. Comparative Effectiveness Review Disposition of Comments Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/bundled-payments-quality-effects_disposition-comments.pdf
      August 24, 2012 - No change in response to this comment because it is a recommendation for future research priorities … We abstracted data on the use of risk-adjustment and any study outcomes related to risk selection or … are a function of use of the wrong measures. … Such studies could examine changes in hospital new technology take-up rates, changes in research and … We include a description of information abstracted from reviewed studies on the use of quality measurement

1290. Evidence-based Practice Center Systematic Review Protocol - Management of Infantile Epilepsies (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-disposition-comments.pdf
      October 25, 2022 - care; clinical guidelines to use when research is not available. … the review, the use of narrow criteria and the grouping together of various types and etiologies of … Even allowing for the problem of the use of this drug under the age of 2 - namely, an increase risk … of serious and potentially fatal adverse reactions - it also has excluded a review of the use of this … Epilepsy Research Foundation on the standard of care for the evaluation and management of infantile

1291. Evidence Summary_Comparative Effectiveness Review No. 255: Transitions of Care From Pediatric to Adult Services for Children With Special Healthcare Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-255-transitions-care-pediatric-to-adult-services-evidence-summary.pdf
      May 01, 2022 - The National Cancer Institute will use our findings to help develop its own independent recommendations … We did not combine data quantitatively due to variability of interventions, comparison groups, outcomes … Studies also used a diverse set of outcome measures to evaluate intervention effects. … Similarly, no single measure or set of measures is used in this body of research. … strategies, generally focused on specific clinical specialties in targeted settings, and none of the

1292. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
      June 01, 2014 - Any investigator or funder of research will be able to use the AHRQ Healthcare Horizon Scanning System … use and costs of any health care technology. … Most research activity in this field focuses on drugs and biologics for irritable bowel syndrome and … An estimated 10,000–20,000 people in the United States receive at-home PN for SBS, based on data from … The REMS program consists of a medication guide, elements to ensure safe use (i.e., provider training

1293. Methods Guide for Medical Test Reviews Chapter 10 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
      July 01, 2012 - This is a distinction between the narrow use of modeling we explore here (to contextualize the findings … Scenario C: Is the available evidence enough to justify the use of PET to identify a group of patients … Hence, we cannot identify a “clear winner” based on test performance data alone. … of test performance data, and in offering insight into the dynamic interplay of various factors on decision-relevant … A pilot study on the use of decision theory and value of information analysis as part of the NHS Health

1294. The series of articles beginning with this issue of the Journal form the most up-to-date version of the Guide for Conducting Comparative Effectiveness Reviews (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-principles_methods.pdf
      August 01, 2009 - existing research on the effectiveness, comparative effectiveness, and harms of different health care … • Inconsistency in the selection of data sources and evaluation of their quality for assessment of … data collection to measure. … range of patient outcomes on decisions to use a medical test, and the assessment of studies of genetic … Undertaking systematic reviews of research on effectiveness (CRD Report 4, 2nd ed).

1295. PKU Surveillance Assessment_CER 56_Low (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_surveillance.pdf
      January 15, 2013 - question the use of the treatment based on evidence of harm or that did not proscribe use entirely … One of the references mentioned by this expert was a guideline recently issued for the use of sapropterin … After 1 year of treatment, the 11 participants discontinued use of a medical food and normalized their … patients were on a protein-restricted diet and the rest were on BH4. 97.7% of the early diagnosed … .59 After 1 year of treatment, the 11 participants discontinued use of a medical food and normalized

1296. Disposition of Comments for Technical Brief 20 Core Functionality in Pediatric Electronic Health Records (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pediatric-ehr_disposition-comments.pdf
      May 01, 2015 - A lot of health care goes on in schools and many if not most schools use EHRs. … There is a significant need to facilitate interprofessional collaboration and use of a core data set … There is a significant need to facilitate interprofessional collaboration and use of a core data set … and with no license to use the underlying data. … license for its use may simply be the lack of awareness of the interest in using data in this way.

1297. Hepatic-Fibrosis White-Paper (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
      April 01, 2014 - of Histological Data in Viral Hepatitis (METAVIR) scale, a score of 3 to 6 on the Ishak scale, or … We considered F4 on the METAVIR scale, a score of 5 to 6 on the Ishak scale, or equivalent to indicate … to the data and need for additional time to find and format the data (e.g., data stored on a floppy … We did not identify a clear pattern for the directional impact of additional data on estimates of diagnostic … The APRI may be enhanced by the use of the FIBROSpect II in the estimation of fibrosis in chronic

1298. Rheumatoid-Arthritis-Medicine Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
      April 01, 2012 - Clinical experience Effective Health Care Program 2 supports the use of MTX as the oral DMARD of … Hand searches were conducted on the Center for Drug Evaluation and Research (CDER) database of the … We designed and used a structured data abstraction form to ensure consistency of appraisal for each … A senior evaluated the completeness of each data abstraction. … The primary efficacy outcome of our MTC meta-analysis was the ACR 50.

1299. Disposition of Comments for Technical Brief 28 MAT Models (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-use-disorder_disposition-comments.pdf
      December 06, 2016 - The need for research on management of patients with opioid use disorder and concomitant pain is included … We revised the bullet on Future Research on management of patients with opioid use disorder and concomitant … We also added a bullet on need for research on optimal medication- assisted treatment models of care … Barriers to use of naltrexone and need for research on naltrexone are noted in the report. … We revised to note the lack of data on rates of utilization of ER naltrexone (p 22) and describe barriers

1300. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
      December 01, 2014 - Any investigator or funder of research will be able to use the AHRQ Healthcare Horizon Scanning System … Most research activity in this field focuses on drugs and biologics for irritable bowel syndrome and … An estimated 10,000–20,000 people in the United States receive at-home PN for SBS, based on data … from the early 1990s (the most recent data), at a cost of more than $100,000 per patient per year. … The REMS program consists of a medication guide, elements to ensure safe use (i.e., provider training