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81. Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
    December 27, 2016 - The SOE approach incorporates five key domains: study limitations, directness, consistency, precision … Additional domains (plausible confounding, dose-response, and magnitude of effect) will be considered … Asthma control is determined by assessing the domains of impairment (patient self-reported symptoms, … Bronchial hyperreactivity/ 6. Reactive airway disease.mp. 7. 1 or 2 or 3 or 4 or 5 or 6 8. … Bronchial hyperreactivity/ 6. Reactive airway disease.mp.

82. celiac-disease-protocol-140612 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
    June 12, 2014 - We will discuss their methods of evaluating the domains described below. … Table 6. … PMID: 23609613. 6. Hill ID, Dirks MH, Liptak GS, et al. … Evid Rep Technol Assess (Summ). 2004 Jun(104):1-6. PMID: 15346868. 9. … Clin Gastroenterol. 2013;47(2):121-6. 11. Chang SM, Matchar DB, al. e.

83. Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
    March 19, 2018 - The specific domains which contributed to the downgrading of all outcomes, organized per KQ, appear … Further description as to the domains that led to downgrading a given outcome are provided in the … The five contributing domains include risk of bias, consistency, directness, precision and publication … ROB was taken into account when SOE was graded, as one of the domains. … ROB was taken into account when SOE was graded, as one of the domains.

84. Behavioral Interventions for Migraine Prevention (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bimp-protocol.pdf
    September 27, 2022 - Third wave CBT • Acceptance and commitment therapy 6. … study and assign a risk of bias rating of “high,” “some concerns,” and “low” for each of the above domains … The primary domains assessed include risk of bias, directness, consistency, precision, and reporting … Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section … PMID: 30600979. 6. American Headache Society.

85. Treatments for Fecal Incontinence: Current State of the Evidence | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/fecal-incontinence/clinician
    December 01, 2019 - Conclusions Evidence to support any fecal incontinence treatments in adults beyond 3 to 6 months is … ; unapproved by the FDA for fecal incontinence treatment) reduced fecal incontinence severity up to 6 … the number of FI episodes over 2 weeks was not significantly different between groups at 3 months or 6 … † The overall evidence grade was assessed based on the ratings for the following domains: study limitations … Other domains that were considered, as appropriate, included dose-response association, plausible confounding

86. Amended Protocol: Management of Infantile Epilepsy (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/infantile-epilepsy-amended-protocol.pdf
    March 07, 2021 - For Key Question 3 (harms), we will include single-arm studies as well as controlled studies. 6. … We will grade the SOE based on the EPC Methods Guide recommendations.4 The primary domains assessed … The rating will be based on considering all of the domains listed below. … Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section … PMID: 2304219. 6. Neinstein LS.

87. A Primer for Systematic Reviewers on the Measurement of Functional Status and Health-Related Quality of Life in Older Adults (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/quality-of-life-functional-status-measurement_white-paper.pdf
    September 01, 2013 - Finally the economics and decision science paradigm, like the clinimetric tradition, selects domains … Correlations for domains of the SF-36 ranged from 0.28 to 0.70; the correlation for EQ-5D scores was … Med Care 1992 Jun;30(6):473-83. 9. Horsman J, Furlong W, Feeny D, et al. … Qual Life Res 2000;9(6):591-601. 54. Brazier J, Roberts J, Tsuchiya A, et al. … Disabil Rehabil 2001 Oct 15;23(15):670-6. 149. Jones CA, Feeny D, Eng K.

88. Meditation Programs for Psychological Stress and Well-Being | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/meditation/research
    December 01, 2019 - Well-Being Systematic Review ARCHIVED Jan 6, … We graded the strength of evidence (SOE) using four domains (risk of bias, precision, directness, and … improvement in anxiety (effect size [ES], 0.40; CI, 0.08 to 0.71 at 8 weeks; ES, 0.22; CI, 0.02 to 0.43 at 3–6 … 0.01 to 0.66 at 8 weeks; ES, 0.23; CI, 0.05 to 0.42 at 3–6 months); and pain (ES, 0.33; CI, 0.03 to 0.62 … Topic Initiated Oct 17, 2012 Research Protocol Archived Jan 6,

89. Evaluation of Dietary Protein Intake Requirements (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
    November 28, 2023 - Bias tool 2.0.21 Risk will be assessed as low, moderate, 8 or high for each of the following domains … will be assessed as low, moderate, serious, critical, or no information for each of the following domains … ROBINS-E) tool23 as low, moderate, serious, critical, or no information for each of the following domains … strength of evidence for outcomes for within each comparison will be evaluated based on five required domains … Sep 6 2003;327(7414):557-60. doi:10.1136/bmj.327.7414.557 28.

90. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amendment.pdf
    February 05, 2025 - study and assign a risk of bias rating of “high,” “some concerns,” or “low” for each of the above domains … Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section … PMID: 36369475. 6. National Survey of Children’s Health. … Mindfulness. 2022;13(2):285-300. doi: 10.1007/s12671-021-01775-6. 32. … GRADE guidelines 6. Rating the quality of evidence-- imprecision.

91. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/ped-mindfulness-protocol-amended.pdf
    September 25, 2024 - study and assign a risk of bias rating of “high,” “some concerns,” or “low” for each of the above domains … In case they are relevant, additional domains, such as dose-response association and strength of association … Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section … PMID: 36369475. 6. National Survey of Children’s Health. … Mindfulness. 2022;13(2):285-300. doi: 10.1007/s12671-021-01775-6. 32.

92. Cannabis-2022-Surv-Rep-3-Table-F5 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-table-F5.xlsx
    January 01, 2022 - NR + 2.85 mg/d 6 months: 3.05 mg/d + 2,295.5 mg/d vs. … NR + 3.02 mg/d 26 (6 months) Short and intermediate A vs. B vs. … B 0.67 (95% CI 0.44 to 1.02) 6 months: 38% (21/49) vs. 48% (31/52) vs. NR, RR for A vs. … C 6 months: 35% (17/49) vs. 60% (31/52) vs. 36% (20/55), RR 0.58 (95% CI 0.37 to 0.91 for A vs. … C Individual SF-36 domains; Individual depression and anxiety domains for HADS; BPI Pain Severity; EQ

93. Cannabis-2022-Update-Surv-Rep-1-App-F-5 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F-5.xlsx
    January 01, 2022 - NR + 2.85 mg/d 6 months: 3.05 mg/d + 2,295.5 mg/d vs. … NR + 3.02 mg/d 26 (6 months) Short and intermediate A vs. B vs. … B 0.67 (95% CI 0.44 to 1.02) 6 months: 38% (21/49) vs. 48% (31/52) vs. NR, RR for A vs. … C 6 months: 35% (17/49) vs. 60% (31/52) vs. 36% (20/55), RR 0.58 (95% CI 0.37 to 0.91 for A vs. … C Individual SF-36 domains; Individual depression and anxiety domains for HADS; BPI Pain Severity; EQ

94. Treatments for Fecal Incontinence | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/fecal-incontinence/research-protocol
    December 01, 2019 - percent of residents with severe cognitive impairment have experienced FI. 4 Monthly FI occurs in 6 … Colorectal Dis 2012; Jun;14(6):e297-304. PMID: 22356165. Glasgow SC, Lowry AC. … Medical care 1992; Jun;30(6):473-83. PMID: 1593914. Rockwood TH, Church JM, Fleshman JW, et al. … Dis Colon Rectum 2001; Jun;44(6):799-805. PMID: 11391139. Williams A. … No Intervention poorly described 6.

95. Supplemental Project To Assess the Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms of Diabetic Peripheral Neuropathy (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
    March 01, 2018 - Strength of evidence domains for studies comparing lacosamide with placebo in terms of quality of life … Strength of evidence domains for studies comparing 8% capsaicin patch with placebo in terms of pain … Neurology. 1998 Jun;50(6):1842-6. PMID: 9633738. 53. . … J Am Podiatr Med Assoc. 1991 Jun;81(6):288-93. doi: 10.7547/87507315-81-6-288. … Lancet. 1988 Jan 2- 9;1(8575-6):9-11. PMID: 2891940. 60.

96. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amended.pdf
    September 25, 2024 - Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section … PMID: 36369475. 6. National Survey of Children’s Health. … Pediatrics. 2016 Dec;138(6) doi: 10.1542/peds.2016-1878. PMID: 27940701. 13. … Mindfulness. 2022;13(2):285-300. doi: 10.1007/s12671-021-01775-6. 32. … GRADE guidelines 6. Rating the quality of evidence-- imprecision.

97. MS Protocol draft_12_12-13 clean[2] (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
    December 17, 2013 - literature, using an instrument we develop based upon the Cochrane Risk of Bias tool.11 The seven domains … outcome data, selective reporting, and other sources of bias (i.e., problems not covered by other domains … to sustained disease progression) within each comparison will be evaluated based on four required domains … an estimate).16 A fifth domain, reporting bias, will be assessed when SOE based upon the first four domains … Q Rev Biol. 2011 Dec;86(4):287-321. 6. Daumer M, Neuhaus A, Herbert J, et al.

98. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
    July 18, 2011 - the randomized controlled trials and nonrandomized controlled trials. 20 The tool examines six domains … The overall assessment is based on the responses to individual domains. … If one or more individual domains are assessed as having a high risk of bias, the overall score will … for Effectiveness and Comparative Effectiveness Reviews. 29 We will examine the following four domains … Rev Neurol (Paris) 2005;161(6-7):658-60. 17.

99. Making Healthcare Safer IV: High Reliability Organization (HRO) as a Patient Safety Practice (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
    January 01, 2023 - Prioritization Report for additional details.1 HROs are organizations that operate in complex, high-hazard domains … When assessing RCTs, we will use the 7 items in the Cochrane Collaboration’s tool that cover the domains … PMID: 37838378. 6. Vogus TJ, Sutcliffe KM, Weick KE. … Crit Care. 2011;15(6):314. PMID: 22188677. 8. Veazie S, Peterson K, Bourne D. … HROs are organizations that operate in complex, high-hazard domains for extended periods without serious

100. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
     June 10, 2024 - Attention-Deficit/Hyperactivity Disorder (ADHD) is characterized by persistent symptoms in the domains … will be influenced by whether the interventions are likely to help the core symptoms of ADHD or other domains … We selected the following domains as key outcomes with input from the technical expert panel: functional … We will evaluate the following domains: • Study limitations: The extent to which studies reporting … The strength of the evidence can be downgraded based on the outlined domains.