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1. Recommendation: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/obstructive-sleep-apnea-in-adults-screening
   November 15, 2022 - 37% to 80% and specificity ranging from 0% to 84% for detecting mild OSA. … the original STOP-BANG questionnaire, both found good sensitivity (87% to 94%) but low specificity (0% … 7 trials, 17% to 74% of participants reported oral mucosal, dental, or jaw symptoms, compared with 0% … In 4 trials, 5% to 33% of participants reported oral dryness, compared with 0% to 3% in control groups … , and in 3 trials, 23% to 68% of participants reported excessive salivation, compared with 0% to 3% in

2. Archived: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/obstructive-sleep-apnea-in-adults-screening-january-2017
   January 24, 2017 - asymptomatic adults (or adults with unrecognized symptoms) to accurately identify who will benefit from … Follow-up in these studies was generally from 4 to 6 weeks. … 7 trials, 17% to 74% of participants reported oral mucosal, dental, or jaw symptoms, compared with 0% … In 4 studies, 5% to 33% of participants reported oral dryness, compared with 0% to 3% in control groups … , and in 3 studies, 23% to 68% of participants reported excessive salivation, compared with 0% to 3%

3. Draft Recommendation: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/obstructive-sleep-apnea-adults-screening
   March 29, 2022 - The Berlin questionnaire had sensitivity ranging from 37% to 80% and specificity ranging from 0% to 84% … the original STOP-BANG questionnaire, both found good sensitivity (87% to 95%) but low specificity (0% … hour blood pressure of -2.63 mm Hg (95% CI, -3.86 to -1.39 mm Hg; 8 trials; 994 participants; I 2 =0% … seven trials, 17% to 74% of participants reported oral mucosal, dental, or jaw symptoms compared with 0% … , and in three trials, 23% to 68% of participants reported excessive salivation compared with 0% to 3%

4. Evidence Summary: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary29/obstructive-sleep-apnea-in-adults-screening
   November 15, 2022 - 25 Specificity of the Berlin Questionnaire was suboptimal for all categories of OSA severity (mild, 0% … (87%), moderate (93%), and severe (94%) OSA but very low specificity for the same subgroups (mild, 0% … and 1, with 0 representing the lowest risk and 1 representing the highest risk. … 5% to 33% in the active MAD group compared with 0% to 3% in the control group. 89 , 120 , 121 , 124 … Sleep Breath . 2007;11(4):239-244. doi:10.1007/s11325-007-0115-0 48.

5. Evidence Summary: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obstructive-sleep-apnea-in-adults-screening
   January 24, 2017 - Statistical significance was assumed when 95% CIs of pooled results did not cross the null (ie, 0 or … The best evidence comes from systematic reviews that reported sensitivities of 93% (pooled estimate from … Mean BMI ranged from 30 to 40. … Limitations (Including Reporting Bias) Quality of Evidence 1: Benefits of screening 0 … Fair to Good 7: Harms of screening or diagnostic testing 0 (NA) NA No studies were identified

6. Final Recommendation Statement: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/obstructive-sleep-apnea-in-adults-screening
   November 15, 2022 - 37% to 80% and specificity ranging from 0% to 84% for detecting mild OSA. … the original STOP-BANG questionnaire, both found good sensitivity (87% to 94%) but low specificity (0% … 7 trials, 17% to 74% of participants reported oral mucosal, dental, or jaw symptoms, compared with 0% … In 4 trials, 5% to 33% of participants reported oral dryness, compared with 0% to 3% in control groups … , and in 3 trials, 23% to 68% of participants reported excessive salivation, compared with 0% to 3% in

7. Archived: Evidence Summary: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obstructive-sleep-apnea-in-adults-screening-january-2017
   January 24, 2017 - Statistical significance was assumed when 95% CIs of pooled results did not cross the null (ie, 0 or … The best evidence comes from systematic reviews that reported sensitivities of 93% (pooled estimate from … Mean BMI ranged from 30 to 40. … Limitations (Including Reporting Bias) Quality of Evidence 1: Benefits of screening 0 … Fair to Good 7: Harms of screening or diagnostic testing 0 (NA) NA No studies were identified

8. Screening for Obstructive Sleep Apnea in Adults: US Preventive Services Task Force Recommendation Statement (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/DxeDM5ywg2J7SwKmETXfbX
   May 01, 2021 - 37% to 80% and specificity ranging from 0% to 84% for detecting mild OSA. … the origi- nal STOP-BANG questionnaire, both found good sensitivity (87% to 94%) but low specificity (0% … -hour blood pressure of −2.63 mm Hg (95% CI, −3.86 to −1.39 mm Hg; 8 trials; 994 participants; I2 = 0% … trials, 17% to 74% of participants re- ported oral mucosal, dental, or jaw symptoms, compared with 0% … , and in 3 trials, 23% to 68% of participants reported exces- sive salivation, compared with 0% to 3%

9. Screening for Obstructive Sleep Apnea in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/Z6Rfj-qwfoMbuLp-hBmhzS
   May 01, 2021 - and 1, with 0 representing the lowest risk and 1 represent- ing the highest risk. … Articles included for KQ3 7 Articles (7 studies) included for KQ2 0 Articles included for KQ1 1086 … NR NR PPV, 89.5 (NR) NPV, 0 (NR) Moderate (AHI 15-29) 92.6 (NR) 18.8 (NR) NR NR PPV, 65.8 (NR) NPV, … compared with 0% to 17% in the sham group, no-treatment group, or conservative management group. … Sleep Breath. 2007;11(4):239-244. doi:10.1007/s11325- 007-0115-0 48.

10. Screening for Obstructive Sleep Apnea (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/6h98_oWrAzFsnXsbjVqtQb
    April 25, 2022 - Screening for Obstructive Sleep Apnea Comment Period from March 29, 2022 to April 25, 2022 … Comments may be submitted from March 29, 2022, to April 25, 2022. … Comment Period from March 29, 2022 to April 25, 2022 … www.uspreventiveservicestaskforce.org/uspstf/index.php/draft-update-summary/obstructive-sleep-apnea-adults-screening Comment Period from

11. U.S. Preventive Services Task Force Issues Draft Recommendation Statement on Screening for Obstructive Sleep Apnea (pdf file)
    www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/obstructive-sleep-apnea-drs-bulletin.pdf
    April 25, 2022 - Comments can be submitted from March 29, 2022, to April 25, 2022, at www.uspreventiveservicestaskforce.org

12. U.S. Preventive Services Task Force Issues Final Recommendation Statement on Screening for Obstructive Sleep Apnea in Adults (pdf file)
    www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/sleep-apnea-screening-final-rec-bulletin.pdf
    November 15, 2022 - draft version of the recommendation statement and evidence review were available for public comment from

13. Draft Research Plan: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/obstructive-sleep-apnea-adults-screening
    December 17, 2020 - search for publications and to determine whether identified studies should be included or excluded from … that include multiple factors (e.g., the multivariable apnea prediction index); may include findings from … designs KQ 2: Questionnaires, tools, and tests not validated in a group of participants separate from

14. Final Research Plan: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obstructive-sleep-apnea-in-adults-screening
    March 04, 2021 - search for publications and to determine whether identified studies should be included or excluded from … that include multiple factors (e.g., the Multivariable Apnea Prediction Index); may include findings from … designs KQ 2: Questionnaires, tools, and tests not validated in a group of participants separate from … Preventive Services Task Force website for public comment from December 17, 2020, to January 20, 2021

15. Final Research Plan: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan142/obstructive-sleep-apnea-in-adults-screening
    October 30, 2014 - The draft Research Plan was available for comment from August 7 until September 3, 2014 at 5:00 p.m., … Moving from left to right, the figure depicts the availability of clinical prediction tools or screening … search for publications and to determine whether identified studies should be included or excluded from … that include multiple factors (e.g., the Multivariable Apnea Prediction Index); may include findings from … Preventive Services Task Force (USPSTF) Web site from August 7 to September 3, 2014.

16. Final Evidence Review: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review/obstructive-sleep-apnea-in-adults-screening
    November 15, 2022 - Share to Facebook Share to X Share to WhatsApp Share to Email Print Final Evidence Review Obstructive Sleep Apnea in Adults: Screening November 15, 2022 Recommendations made by the USPSTF are independent of the U.S. government. They should not b…

17. Screening for Obstructive Sleep Apnea in Adults: Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rm4E5SooP2GnqJ_HVRA5M4
    January 01, 2017 - Statistical significance was assumed when 95% CIs of pooled results did not cross the null (ie, 0 or … Summary of Evidence Search and Selection 8398 Citations excluded based on review of title and abstract 0 … included for KQ4 50 Studies (58 articles) included for KQ5 11 Studies (12 articles) included for KQ6 0 … Applicability Limitations (Including Reporting Bias) Quality of Evidence 1: Benefits of screening 0 … Fair to Good 7: Harms of screening or diagnostic testing 0 (NA) NA No studies were identified that

18. Archived: Final Research Plan: Obstructive Sleep Apnea in Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan142/obstructive-sleep-apnea-in-adults-screening-january-2017
    October 30, 2014 - The draft Research Plan was available for comment from August 7 until September 3, 2014 at 5:00 p.m., … Moving from left to right, the figure depicts the availability of clinical prediction tools or screening … search for publications and to determine whether identified studies should be included or excluded from … that include multiple factors (e.g., the Multivariable Apnea Prediction Index); may include findings from … Preventive Services Task Force (USPSTF) Web site from August 7 to September 3, 2014.

19. Screening for Obstructive Sleep Apnea in Adults (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/VwvmgA5bLZZJhK6YSqRonU
    November 01, 2022 - Screening for Obstructive Sleep Apnea in Adults The USPSTF recognizes that clinical decisions involve more considerations than evidence alone. Clinicians should understand the evidence but individualize decision making to the specific patient or situation. Clinician Summary of USPSTF Recommendation Screening…

20. PII: S0749-3797(01)00255-0 (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/yw_rbA_nQrCnkaN8X5t56S
    January 01, 2001 - PII: S0749-3797(01)00255-0 Screening and Treating Adults for Lipid Disorders Michael P. … PII S0749-3797(01)00255-0 Introduction Elevated low-density lipoprotein cholesterol(LDL-C) and low … ) 100 100 100 85 White (%) 95.5 ;100 ;100 89 Mean BMI (kg/m2) 26.25 26.6 26 27.05 Hypertension (%) 0 … 150 Mean HDL start (mg/dL) 45 47 44 Men, 36 Women, 40 Current smokers (%) 38 36 44 12.5 Angina (5) 0 … 0 5 0 Diabetes 0 2.65 1 2.5 ASA use (%) NR NR 3 17 LRC, Lipids Research Council; HHS, Helsinki Heart