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121. Topic-Brief3-Sud (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
     April 01, 2021 - This topic development brief is part of the Dr. … of opioid use disorder in this age group appears to be increasing; data indicates that first time OUD … Chronic pain among patients with opioid use disorder: Results from electronic health records data. … The information in this report is intended to help health care decision makers—patients and clinicians … This report is not intended to be a substitute for the application of clinical judgment.

122. Topic-Brief3-Sud (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief3-SUD.pdf
     April 01, 2021 - This topic development brief is part of the Dr. … of opioid use disorder in this age group appears to be increasing; data indicates that first time OUD … Chronic pain among patients with opioid use disorder: Results from electronic health records data. … The information in this report is intended to help health care decision makers—patients and clinicians … This report is not intended to be a substitute for the application of clinical judgment.

123. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
     November 01, 2013 - This report is based on research conducted by the RTI International-University … Lastly, we acknowledge with gratitude the expert document preparation provided by Loraine Monroe at … For the directness domain, this is the most desirable situation. 11 In many circumstances, such … EPCs should record information describing applicability for the outcomes and comparisons for which … We posit four main criteria for making this decision: at least 10 studies contribute data for the outcome

124. Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
     December 31, 2022 - tests available in the United States.5 4 Purpose This is the final update for … in the finding that prior infection provided weaker protection against reinfection by the Omicron variant … Disclaimers This report is based on research conducted by the Scientific Resource Center for the AHRQ … Role of the Funding Source: Funding for this review was provided by AHRQ. … Questions for This Update What Is New?

125. Disposition of Comments for CER 196 The Role of Immunotherapy in the Treatment of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-196-disposition-comments-immunotherapy-asthma.pdf
     March 23, 2018 - Each comment is listed with the name and affiliation of the commentator, if this information is provided … provided data specific to those with asthma. … provided data specific to those with asthma. … not provided in this review. … Further, anaphylaxis, defined by the NIAID (Sampson et al.), for all practical purposes, involves hypotension

126. Ch-7-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch-7-user-guide-to-ocer_130129.pdf
     March 29, 2012 - The purpose of this chapter is to address the complex issue of selecting variables for adjustment in … This is illustrated in Figure 7.5. … does not know which subset this is), the disjunctive cause criterion when applied correctly by the … hundreds, if not thousands, of data points that are recorded for clinical and administrative purposes … Advances in computer performance and the availability of high- dimensional data have provided unprecedented

127. Future Research Needs for Hematopoietic Stem-Cell Transplantation in the Pediatric Population (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
     February 01, 2012 - This information is provided for researchers and funders of research in these Future Research Needs … They kept the Key Questions broad for the purposes of this report as data are too sparse to focus on … However, for the purposes of this review, we considered it 4 methodological issue, which would … They kept the Key Questions broad for the purposes of this report, as they felt that data are too sparse … Psychological services in this design will be provided by the centers.

128. Ace-Inhibitor-Arb-Update-Surveillance-160328 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
     October 08, 2025 - ,"we"did" not"include"a"column"for"this"in"the"summary"table." … "" " " The"signal"for"this"report"is"medium"suggesting"that"the"conclusions"in"the"original"systematic … $Abstracts$are$provided$for$included$literature$at$the$end$of$the$document.$ $ Conclusions&From&Original … $Medical$records$data$were$extracted$and$linked$with$nationwide$hospital$discharge$ and$cause$of$death … $There$is$a$lack$of$data$ supporting$the$use$of$azilsartan$for$improvement$in$cardiovascular$outcomes

129. Covariate Selection for Observational Comparative Effectiveness Research
     effectivehealthcare.ahrq.gov/sites/default/files/covariate-selection-chapter-7.pptx
     January 01, 2013 - statistical associations observed in the data. … Z-bias arises when the variable set is insufficient to remove all confounding; for this reason, Z-bias … This is what amplifies the residual confounding bias. … provided the effect of the confounder on the treatment and the outcome are “monotonic.” … the strengths and weaknesses of the data source (e.g., administrative claims, electronic medical records

130. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
     January 01, 2012 - Consistent with the definitions of health care interventions provided by the Institute of Medicine … Send comments by mail to the Task Order Officer named in this report to: Agency for Healthcare Research … The material on interventions in this Executive Summary and report is organized alphabetically by disease … Based on this input, our overall assessment is that this intervention is in the lower end of the high-potential … Based on this input, our overall assessment is that this intervention is in the higher end of the high

131. Disposition of Comments for Technical Brief 27 Patient Safety (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ambulatory-safety_disposition-comments.pdf
     October 19, 2016 - Each comment is listed with the name and affiliation of the commentator, if this information is provided … report is overall sound largely confirming what is known by experts in this terrain - it is nonetheless … Yes, clearly describes how data for this report was gathered. … Peer Reviewer #3 Methods This section clearly and concisely describes how data for the report was gathered … Certainly they were limited by the nature of the fragmentary data that is out there, but one would've

132. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infertility_research-protocol.pdf
     October 12, 2015 - is women who donate oocytes for use by other couples in ART. … data on U.S. population-based outcomes for ART, it is limited by (a) use of the ART cycle (rather than … Our proposed search strategy for PubMed® is provided in Table 2; this strategy will be adapted as appropriate … We will design the data abstraction forms for this project to collect the data required to evaluate … the specified eligibility criteria for inclusion in this review, as well as demographic and other data

133. Disposition of Comments Report for Treatment of Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
     June 28, 2013 - This is not supported by the data we have in RACE-II. … by the data presented. … Also in this Table, if the CI is provided there is no reason to say that difference is statistically … Unfortunately, our systematic review is limited in that we must use the information provided by authors … In addition, the data is insufficient for this specific comparison/outcome.

134. Liver-Cancer Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
     October 01, 2014 - The purpose of this report is to comprehensively review the comparative effectiveness and diagnostic … in the AHRQ “Methods Guide for Medical Test Reviews,”9 which is based on methods developed by the … for each Key Question was assessed by one researcher for each outcome described in the PICOTS using … Almost all studies reported sensitivity, but only 130 reported specificity or provided data to calculate … This is probably related to the short duration in which microbubble contrast is present within the liver

135. Systematic Review on Acute Treatments for Episodic Migraine: Surveillance Report 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
     June 01, 2022 - through September 2021 Background and Purpose This report is the first update for the Agency for … in the final update, which is scheduled for June 2022. … Eptinezumab was not included in the 2020 report, and these new data provide moderate SOE for this treatment … No studies in the original report evaluated these options, and there is low SOE for this new evidence … Disclaimers This report is based on research conducted by the Mayo Clinic Evidence-based Practice Center

136. Disposition of Comments Report for Technical Brief 14 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-survivor-care-transition_disposition-comments.pdf
     March 18, 2014 - defined by the authors based on the IOM report, seems premature given the lack of empiric data in this … The definition provided by the authors that this concerns, “a program for survivors that addresses … , and therapies is provided by payers. … and that there is a paucity of data evaluating outcomes of care provided in these models. … In the glossary the definition of survivor might be better qualified as “for the purposes of this brief

137. Work Plan for Methods Research on (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
     December 01, 2010 - Note that this tool is no longer advocated by the NRSMG, • A tool developed by the American Dietetic … purposes of this project. … A common method for data collection is a survey. … A common method for data collection is a survey. … records.

138. Heart-Failure-Natriuretic-Peptide Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
     November 01, 2013 - model developed by van Houwelingen16,17 and modified for synthesis of diagnostic test data.18 The … record. … For BNP, we present data on the common cutpoint of 100 pg/mL proposed by all manufacturers of FDA- approved … Currently, the data from the studies that have evaluated BNP or NT-proBNP for this purpose are inconclusive … not provided for variance data in any study.

139. Disposition of Comments for Treatment of Glaucoma: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_disposition-comments.pdf
     April 01, 2012 - Each comment is listed with the name and affiliation of the commentator, if this information is provided … Although they correctly note that there are few data on this subject, publications by Weinreb et al. … for the harms data? … This does not involve the data itself, but, rather, how the data are presented and executive summary … In fact, where data is available (eg OHTS), the data supports current consensus- and evidence-driven

140. Comparative Effectiveness Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bundled-payments-quality-effects_disposition-comments.pdf
     August 24, 2012 - Each comment is listed with the name and affiliation of the commentator, if this information is provided … may have been fine for the purposes for which they were written. … price of a bundle is determined and by whom is a critical issue, but this is typically mentioned in … Evaluation should include analysis of patient medical records, not simply claims data, and a comparison … about why the review is limited and what they think can be gleaned from it for the purposes of policy